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Bioactivity-guided synthesis of gramine derivatives as new MT1 and 5-HT1A receptors agonists 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 卷号: 19, 期号: 6, 页码: 610-622
作者:  Yin, Xiu-Juan;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Geng, Chang-An;  Li, Tian-Ze;  Chen, Xing-Long;  Yang, Tong-Hua;  Zhou, Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2718Kb)  |  收藏  |  浏览/下载:316/57  |  提交时间:2017/07/10
Gramine  Melatonin Receptor  5-hydroxy-tryptamine Receptor  Agonistic Activity  Structure-activity Relationships  
Three new anti-HBV active constituents from the traditional Chinese herb of Yin-Chen (Artemisia scoparia) 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2015, 卷号: 176, 页码: 109-117
作者:  Geng, Chang-An;  Huang, Xiao-Yan;  Chen, Xing-Long;  Ma, Yun-Bao;  Rong, Guang-Qing;  Zhao, Yong;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2656Kb)  |  收藏  |  浏览/下载:542/52  |  提交时间:2016/02/01
Artemisia Scoparia (Yin-chen)  4-pyridone Glycoside  Polyacetylenes  Anti-hbv Activity  Lcms  
Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载:291/72  |  提交时间:2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
Swerpunilactones A and B, the first example of xanthone and secoiridoid heterodimers from Swertia punicea, S. hispidicalyx, and S. yunnanensis 期刊论文
TETRAHEDRON LETTERS, 2013, 卷号: 54, 期号: 21, 页码: 2710-2712
作者:  Wang, Hong-Ling;  Cao, Tuan-Wu;  Jiang, Fu-Qiang;  Geng, Chang-An;  Zhang, Xue-Mei;  Huang, Xiao-Yan;  Wang, Li-Jun;  Kang-He, Sing Wd;  Hao-Chen;  Liang, Wen-Juan;  Rong, Guang-Qing;  Chen, Ji-Jun
Adobe PDF(393Kb)  |  收藏  |  浏览/下载:476/133  |  提交时间:2013/06/08
Swerpunilactones A-b  Anti-hbv Activity  Swertia Punicea  Swertia Hispidicalyx  Swertia Yunnanensis  
Small-Molecule Inhibitors for the Treatment of Hepatitis B Virus Documented in Patents 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 5, 页码: 749-776
作者:  Geng, Chang-An;  Wang, Li-Jun;  Guo, Rui-Hua;  Chen, Ji-Jun
Adobe PDF(616Kb)  |  收藏  |  浏览/下载:347/129  |  提交时间:2013/06/08
Hepatitis b Virus (Hbv)  Small-molecule Inhibitors  Nucleoside Analogs  Non-nucleosides  Natural Products  Synthesized Compounds  Chemical Modification  Patents