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The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：259/1  |  提交时间：2017/07/24
The dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2-dependent and -independent fever while 4-AA only blocks PGE2-dependent fever1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
作者:  David do C. Malvar;  Fernando A. Aguiar;  Artur de L. L. Vaz;  Débora C. R. Assis;  Miriam C. C. de Melo;  Valquíria A. P. Jabor;  Evanguedes Kalapothakis;  Sérgio H. Ferreira;  Giuliano C. Clososki;  Glória E. P. de Souza
Adobe PDF(2243Kb)  |  收藏  |  浏览/下载：283/1  |  提交时间：2017/07/24
Dipyrone  Dipyrone Metabolites  Fever  Hypothermia  Lps  Tityus Serrulatus Venom  
Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins 期刊论文
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
作者:  Pauline Macheboeuf;  Delphine S Fischer;  Tom Brown Jr;  Astrid Zervosen;  Andre´Luxen;  Bernard Joris;  Andrea Dessen;  Christopher J Schofield
Adobe PDF(425Kb)  |  收藏  |  浏览/下载：79/1  |  提交时间：2017/07/21
Increased Catalytic Efficiency following Gene Fusion of Bifunctional MethionineSulfoxide Reductase Enzymes from Shewanella oneidensis 期刊论文
Biochemistry, 3111, 页码: 1—9
作者:  C.B. Li;  D.M. Zhang;  S. Ge;  D.Y. Hong
Adobe PDF(436Kb)  |  收藏  |  浏览/下载：101/1  |  提交时间：2017/07/19
The pharmacokinetics of anthocyanins and their metabolites in humans 期刊论文
出版物, 3111, 期号: 0, 页码: 1-37
作者:  R M de Ferrars;  C Czank;  Q Zhang;  N P Botting;  P A Kroon;  A Cassidy;  C D Kay
Adobe PDF(1873Kb)  |  收藏  |  浏览/下载：117/1  |  提交时间：2017/07/24
Anthocyanins  Metabolites  Hippuric Acid  Ferulic Acid  Vanillic Acid  
Unravelling the key aroma compounds in the characteristic fragrance of Dendrobium officinale flowers for potential industrial application 期刊论文
PHYTOCHEMISTRY, 2022, 卷号: 200, 页码: 8
作者:  Yang, Yu-Han;  Zhao, Jie;  Du, Zhi-Zhi
浏览  |  Adobe PDF(2469Kb)  |  收藏  |  浏览/下载：211/5  |  提交时间：2022/07/15
Dendrobium officinale  Orchidaceae  Aroma-active compounds  Solvent-assisted flavor evaporation  Progressive addition test  Aroma profile reconstruction  
Metabolomics reveals metabolite changes of patients with pulmonary arterial hypertension in China 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2020, 页码: 13
作者:  Chen, Chenyang;  Luo, Fei;  Wu, Panyun;  Huang, Yiyuan;  Das, Avash;  Chen, Shenglan;  Chen, Jingyuan;  Hu, Xinqun;  Li, Fei;  Fang, Zhenfei;  Zhou, Shenhua
收藏  |  浏览/下载：89/0  |  提交时间：2020/03/18
lipid metabolism  metabolomics  pulmonary arterial hypertension  
Identification and Characterization of ShSPI, a Kazal-Type Elastase Inhibitor from the Venom of Scolopendra Hainanum 期刊论文
TOXINS, 2019, 卷号: 11, 期号: 12, 页码: 13
作者:  Luan, Ning;  Zhao, Qiyu;  Duan, Zilei;  Ji, Mengyao;  Xing, Meichen;  Zhu, Tengyu;  Mwangi, James;  Rong, Mingqiang;  Liu, Jiangxin;  Lai, Ren
浏览  |  Adobe PDF(2415Kb)  |  收藏  |  浏览/下载：144/28  |  提交时间：2020/03/18
centipede  kazal-type inhibitor  human neutrophils elastase  ShSPI  
Leucosceptroid B from glandular trichomes of Leucosceptrum canum reduces fat accumulation in Caenorhabditis elegans through suppressing unsaturated fatty acid biosynthesis 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 892-899
作者:  Ling Yi;  Teng Lin-Lin;  Hua Juan;  Li De-Sen;  Luo Shi-Hong;  Liu Yan-Chun;  Liu Yan;  Li Sheng-Hong
浏览  |  Adobe PDF(1517Kb)  |  收藏  |  浏览/下载：231/45  |  提交时间：2020/03/18
Sesterterpenoid  Leucosceptroid B  Leucosceptrum canum  Caenorhabditis elegans  Fat accumulation  Fatty acid biosynthesis  Antilipemic agent  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：156/28  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine