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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
作者:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  收藏  |  浏览/下载:238/1  |  提交时间:2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载:258/1  |  提交时间:2017/07/24
Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins 期刊论文
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
作者:  Pauline Macheboeuf;  Delphine S Fischer;  Tom Brown Jr;  Astrid Zervosen;  Andre´Luxen;  Bernard Joris;  Andrea Dessen;  Christopher J Schofield
Adobe PDF(425Kb)  |  收藏  |  浏览/下载:79/1  |  提交时间:2017/07/21
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
作者:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  收藏  |  浏览/下载:274/1  |  提交时间:2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin 期刊论文
出版物, 3111, 期号: 0, 页码: 1-62
作者:  M Iijima;  T Yoshimizu;  T Shimazaki;  K Tokugawa;  K Fukumoto;  S Kurosu;  T Kuwada;  Y Sekiguchi;  S Chaki
Adobe PDF(776Kb)  |  收藏  |  浏览/下载:101/2  |  提交时间:2017/07/24
Arginine Vasopressin  V1b Receptor Antagonist  Depression  Anxiety  Hpa Axis  
Nociceptin/Orphanin FQ peptide receptor antagonist JTC-801 reverses pain and anxiety symptoms in a rat model of PTSD 期刊论文
出版物, 3111, 期号: 0, 页码: 1-33
作者:  Y Zhang;  C D Simpson-Durand;  K M Standifer
Adobe PDF(1098Kb)  |  收藏  |  浏览/下载:99/1  |  提交时间:2017/07/24
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
作者:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
Adobe PDF(1611Kb)  |  收藏  |  浏览/下载:89/1  |  提交时间:2017/07/24
Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
Synthesis and antitumor activity of novel N-substituted tetrahydro-β-carboline–imidazolium salt derivatives 期刊论文
Org. Biomol. Chem., 2016, 卷号: 14, 页码: 9423
作者:  Bei Zhou
Adobe PDF(1764Kb)  |  收藏  |  浏览/下载:41/0  |  提交时间:2017/08/23
Design, Synthesis, and Biological Evaluation of Novel Benzofuran Derivatives Bearing N-Aryl Piperazine Moiety 期刊论文
Molecules, 2016, 卷号: 21, 页码: 1684
作者:  Yulu Ma
Adobe PDF(907Kb)  |  收藏  |  浏览/下载:45/0  |  提交时间:2017/08/21
Design, synthesis and anticancer activity of novel hybrid compounds between benzofuran and N-aryl piperazine 期刊论文
Bioorganic & Medicinal Chemistry Letters, 2016, 卷号: 24, 页码: 3421–3424
作者:  Ze-Wei Mao
Adobe PDF(1547Kb)  |  收藏  |  浏览/下载:42/0  |  提交时间:2017/08/18