中文版 | English

在结果中检索

KIB OpenIR

浏览/检索结果: 共15条，第1-10条 帮助

限定条件                
已选(0)清除 条数/页：   排序方式：
Redox Dual-Responsive and O-2-Evolving Theranostic Nanosystem for Highly Selective Chemotherapy against Hypoxic Tumors 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 1, 页码: 90-103
作者:  Chen, Huachao;  Li, Fei;  Yao, Yongrong;  Wang, Zhe;  Zhang, Zhihao;  Tan, Ninghua
浏览  |  Adobe PDF(3409Kb)  |  收藏  |  浏览/下载：162/44  |  提交时间：2019/07/29
cancer  theranostic system  hypoxic tumor  ROS/GSH dual-activatable  cyclopeptide RA-V  fluorescence imaging  
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 11, 页码: UNSP 1934
作者:  Song, Lihua;  Wang, Zhe;  Wang, Yurong;  Guo, Di;  Yang, Jianhong;  Chen, Lijuan;  Tan, Ninghua
浏览  |  Adobe PDF(4110Kb)  |  收藏  |  浏览/下载：128/29  |  提交时间：2018/05/08
Ra-xii  Cyclopeptide  Autophagy  Apoptosis  Mtor  Hepg2 Liver Cancer Cells  
New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: 1, 页码: 1
作者:  Yue, Grace Gar-Lee;  Xie, Sida;  Lee, Julia Kin-Ming;  Kwok, Hin-Fai;  Gao, Si;  Nian, Yin;  Wu, Xiao-Xiao;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
Adobe PDF(2501Kb)  |  收藏  |  浏览/下载：243/46  |  提交时间：2016/12/21
Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N-9-Methyl Group in the Conformation and Bioactivity 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 12
作者:  Wang, Zhe;  Zhao, Si-Meng;  Zhao, Li-Mei;  Chen, Xiao-Qiang;  Zeng, Guang-Zhi;  Tan, Ning-Hua
Adobe PDF(805Kb)  |  收藏  |  浏览/下载：688/179  |  提交时间：2016/02/01
Fibulin-3 is a novel TGF-beta pathway inhibitor in the breast cancer microenvironment 期刊论文
ONCOGENE, 2015, 卷号: 34, 期号: 45, 页码: 5635-5647
作者:  Tian,H.;  Liu,J.;  Chen,J.;  Gatza,M. L.;  Blobe,G. C.
Adobe PDF(7351Kb)  |  收藏  |  浏览/下载：113/34  |  提交时间：2016/01/19
Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-kappa B signaling pathways 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2015, 卷号: 1853, 期号: 8, 页码: 1827-1840
作者:  Leung, Hoi-Wing;  Wang, Zhe;  Yue, Grace Gar-Lee;  Zhao, Si-Meng;  Lee, Julia Kin-Ming;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Lau, Clara Bik-San;  Tan, Ning-Hua;  Lau,CBS (reprint author),Chinese Univ Hong Kong,Inst Chinese Med,Shatin,Hong Kong,Peoples R China.;  claralau@cuhk.edu.hk;  nhtan@mail.kib.ac.cn
Adobe PDF(2434Kb)  |  收藏  |  浏览/下载：271/44  |  提交时间：2015/07/20
Cyclopeptide  Cell Adhesion  Cell Invasion  Metastasis  Breast Cancer  
Processing and chemical constituents of Pu-erh tea: A review 期刊论文
FOOD RESEARCH INTERNATIONAL, 2013, 卷号: 53, 期号: 2, 页码: 608-618
作者:  Lv, Hai-peng;  Zhang, Ying-jun;  Lin, Zhi;  Liang, Yue-rong
Adobe PDF(1642Kb)  |  收藏  |  浏览/下载：1761/538  |  提交时间：2013/11/12
Pu-erh Tea  Chemical Constituents  Processing  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
浏览  |  Adobe PDF(6299Kb)  |  收藏  |  浏览/下载：211/42  |  提交时间：2015/05/14
One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.  
Plant cyclopeptide RA-V kills human breast cancer cells by inducing mitochondria-mediated apoptosis through blocking PDK1-AKT interaction 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2013, 卷号: 267, 期号: 1, 页码: 95-103
作者:  Fang, Xian-Ying;  Chen, Wei;  Fan, Jun-Ting;  Song, Ran;  Wang, Lu;  Gu, Yan-Hong;  Zeng, Guang-Zhi;  Shen, Yan;  Wu, Xue-Feng;  Tan, Ning-Hua;  Xu, Qiang;  Sun, Yang
浏览  |  Adobe PDF(1855Kb)  |  收藏  |  浏览/下载：720/122  |  提交时间：2013/03/18
Ra-v  Cyclopeptide  Mitochondrial Apoptosis Pathway  Pi3k/akt  Breast Cancer  
Anti-angiogenesis and immunomodulatory activities of an anti-tumor sesquiterpene bigelovin isolated from Inula helianthus-aquatica 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 59, 页码: 243-252
作者:  Yue, Grace G. L.;  Chan, Ben C. L.;  Kwok, Hin-Fai;  Wong, Yuk-Lau;  Leung, Hoi-Wing;  Ji, Chang-Jiu;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Tan, Ning-Hua;  Lau, Clara B. S.
浏览  |  Adobe PDF(1804Kb)  |  收藏  |  浏览/下载：153/41  |  提交时间：2015/05/12
Bigelovin  Inula Helianthus-aquatica  Angiogenesis  Zebrafish  Hmec-1  Cell Adhesion Molecules