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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载:136/0  |  提交时间:2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Benwamycins A-G, Trialkyl-Substituted Benzene Derivatives from a Soil-Derived Streptomyces 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020, 卷号: 83, 期号: 1, 页码: 111-117
作者:  Yang, Feng-Xian;  Huang, Jian-Ping;  Liu, Zhixiang;  Wang, Zhiyan;  Yang, Jing;  Tang, Jun;  Yu, Zhiyin;  Yan, Yijun;  Kai, Guoyin;  Huang, Sheng-Xiong
收藏  |  浏览/下载:143/0  |  提交时间:2020/03/24
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
浏览  |  Adobe PDF(2215Kb)  |  收藏  |  浏览/下载:163/47  |  提交时间:2020/03/18
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
浏览  |  Adobe PDF(1542Kb)  |  收藏  |  浏览/下载:207/73  |  提交时间:2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Leucosceptroid B from glandular trichomes of Leucosceptrum canum reduces fat accumulation in Caenorhabditis elegans through suppressing unsaturated fatty acid biosynthesis 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 892-899
作者:  Ling Yi;  Teng Lin-Lin;  Hua Juan;  Li De-Sen;  Luo Shi-Hong;  Liu Yan-Chun;  Liu Yan;  Li Sheng-Hong
Adobe PDF(1517Kb)  |  收藏  |  浏览/下载:219/45  |  提交时间:2020/03/18
Sesterterpenoid  Leucosceptroid B  Leucosceptrum canum  Caenorhabditis elegans  Fat accumulation  Fatty acid biosynthesis  Antilipemic agent  
Structural determination of eleven new preschisanartane-type schinortriterpenoids from two Schisandra species and structural revision of preschisanartanin J using NMR computation method 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 970-981
作者:  Hu Kun;  Li Xing-Ren;  Tang Jian-Wei;  Li Xiao-Nian;  Puno, Pema-Tenzin
Adobe PDF(1250Kb)  |  收藏  |  浏览/下载:130/41  |  提交时间:2020/03/18
Schisandra sphaerandra  Schisandra rubriflora  Preschisanartane-type schinortriterpenoids  Structural revision  Quantum chemical calculation of NMR parameters  
Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 22, 页码: 9272-9275
作者:  Zhang, Yu;  Ding, Xiao;  Shao, Shun;  Guo, Ling-Li;  Zhao, Qing;  Hao, Xiao-Jiang;  He, Hong-Ping
Adobe PDF(982Kb)  |  收藏  |  浏览/下载:254/147  |  提交时间:2020/03/02
Tacamine-type alkaloids from Tabernaemontana bovina together with their configuration determination 期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 40, 页码: 7
作者:  Yu, Yang;  Bao, Fen;  Wang, Yi;  Zeng, Ying;  Cai, Xiang-Hai
Adobe PDF(1051Kb)  |  收藏  |  浏览/下载:165/35  |  提交时间:2019/12/20
Tabernaemontana bovina  Tacamine alkaloids  Tabercamines A-K  Configuration determination  
Zingiberols A-C, three rare diterpenols and their cytotoxicities from Zingiber mioga 期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 33, 页码: 106-109
作者:  Li, Zheng-Hui;  Bai, Xue;  Du, Jiao-Xian;  Li, Jia-Yi;  He, Juan;  Ai, Hong-Lian
Adobe PDF(1027Kb)  |  收藏  |  浏览/下载:139/47  |  提交时间:2019/12/20
Zingiber mioga  Diterpenols  Zingiberols A-C  Cytotoxicity  
Melotenuines A-E, cytotoxic monoterpenoid indole alkaloids from Melodinus tenuicaudatus 期刊论文
FITOTERAPIA, 2019, 卷号: 138, 页码: 7
作者:  Liu, Jian-Wen;  Huo, Zong-Qing;  Zhao, Qian;  Hao, Xiao-Jiang;  He, Hong-Ping;  Zhang, Yu
浏览  |  Adobe PDF(435Kb)  |  收藏  |  浏览/下载:271/188  |  提交时间:2020/03/18
Melodinus tenuicaudatus  Monoterpenoid indole alkaloids  Melotenuines A-E  Aspidosperma-meloscandonine type