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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
浏览  |  Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：319/74  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 8, 页码: 1884-1888
作者:  Yan, Chen;  Huang, Li;  Liu, Hong-Chun;  Chen, Duo-Zhi;  Liu, Hai-Yang;  Li, Xiao-Hui;  Zhang, Yu;  Geng, Mei-Yu;  Chen, Quan;  Hao, Xiao-Jiang
Adobe PDF(1562Kb)  |  收藏  |  浏览/下载：270/41  |  提交时间：2014/06/23
Spiramine Derivative  Bax(-/-)/bak(-/-) Cells  Alpha  Apoptosis  Beta-unsaturated Ketone  Cytotoxicity  
Cytotoxic cardiac glycosides and coumarins from Antiaris toxicaria 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 6, 页码: 1889-1898
作者:  Shi, Li-Shian;  Kuo, Sheng-Chu;  Sun, Han-Dong;  Morris-Natschke, Susan L.;  Lee, Kuo-Hsiung;  Wu, Tian-Shung
Adobe PDF(537Kb)  |  收藏  |  浏览/下载：491/54  |  提交时间：2014/05/16
Antiaris Toxicaria  Cardiac Glycosides  Coumarins  Cytotoxicity  
Antiproliferative Cardiac Glycosides from the Latex of Antiaris toxicaria 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 9, 页码: 1771-1780
作者:  Liu, Qian;  Tang, Jin-Shan;  Hu, Meng-Jie;  Liu, Jie;  Chen, Hai-Feng;  Gao, Hao;  Wang, Guang-Hui;  Li, Shun-Lin;  Hao, Xiao-Jiang;  Zhang, Xiao-Kun;  Yao, Xin-Sheng
浏览  |  Adobe PDF(2429Kb)  |  收藏  |  浏览/下载：193/89  |  提交时间：2015/05/13
Development of novel conformation-constrained cytotoxic derivatives of cheliensisin A by embedment of small heterocycles 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 9, 页码: 4238-4244
作者:  Deng, Xu;  Su, Jia;  Zhao, Yu;  Peng, Li-Yan;  Li, Yan;  Yao, Zhu-Jun;  Zhao, Qin-Shi
Adobe PDF(450Kb)  |  收藏  |  浏览/下载：375/96  |  提交时间：2012/03/16
Cheliensisin a  Derivative  Structure-activity Relationship  Cytotoxicity  Anticancer  
Cytotoxic ent-kaurane diterpenoids from Isodon sinuolata 期刊论文
PHYTOCHEMISTRY, 2009, 卷号: 70, 期号: 11-12, 页码: 1462-1466
作者:  He, Fei;  Xiao, Wei-Lie;  Pu, Jian-Xin;  Wu, Ying-Li;  Zhang, Hai-Bo;  Li, Xiao-Nian;  Zhao, Yong;  Yang, Li-Bin;  Chen, Guo-Qiang;  Sun, Han-Dong
Adobe PDF(297Kb)  |  收藏  |  浏览/下载：286/93  |  提交时间：2012/03/21
Isodon Sinuolata  Labiatae  Diterpenoids  Cytotoxicity  
A novel lignanoid and norbisabolane sesquiterpenoids from Glochidion puberum 期刊论文
CHEMISTRY OF NATURAL COMPOUNDS, 2008, 卷号: 44, 期号: 5, 页码: 588-590
作者:  Liu, Min;  Xiao, Hai-Tao;  He, Hong-ping;  Hao, Xiao-Yan
Adobe PDF(265Kb)  |  收藏  |  浏览/下载：295/101  |  提交时间：2012/10/12
Glochidion Puberum  Lignanoid  Glochinin a  Norbisabolane Sesquiterpenoid  
Isolation of two bioactive ent-Kauranoids from the leaves of Isodon xerophilus 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2007, 卷号: 55, 期号: 15, 页码: 6039-6043
作者:  Weng, Zhi-Ying;  Huang, Sheng-Xiong;  Li, Ma-Lin;  Zeng, Yue-Qin;  Han, Quan-Bin;  Rios, Jose Luis;  Sun, Han-Dong
Adobe PDF(93Kb)  |  收藏  |  浏览/下载：354/119  |  提交时间：2012/10/12
Anti-inflammation  Cytotoxicity  Herbal Tea  Isodon Xerophilus  Ent-kaurene Diterpenoid  
Synthesis and cytotoxicity of some new eriocalyxin B derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 卷号: 42, 期号: 4, 页码: 494-502
作者:  Zhao, Yu;  Niu, Xue-Mei;  Qian, Li-Ping;  Liu, Ze-Yuan;  Zhao, Qin-Shi;  Sun, Han-Dong
Adobe PDF(329Kb)  |  收藏  |  浏览/下载：308/114  |  提交时间：2011/11/24
Eriocalyxin b  Synthesis  Cytotoxicity  Sar