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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
作者:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  收藏  |  浏览/下载：135/1  |  提交时间：2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
Olmesartan prevents cardiac rupture in mice with myocardial infarction by modulating growth differentiation factor 15 and P53 期刊论文
出版物, 3111, 期号: 0, 页码: 1-37
作者:  Baihe Chen;  Di Lu;  Yujuan Fu;  Jingwen Zhang;  Xiaobo Huang;  Shiping Cao;  Dingli Xu;  Jianping Bin;  Masafumi Kitakaze;  Qiaobing Huang;  Yulin Liao
Adobe PDF(1769Kb)  |  收藏  |  浏览/下载：262/1  |  提交时间：2017/07/24
Cardiac Rupture  Olmesartan  P53  Gdf-15  Aldosterone  Myocardial Infarction  
Termitomenins F and G, Two New Lignan Glucosides from Terminalia chebula var. tomentella (Kurz) C. B. Clarke. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 5, 页码: 565-572
作者:  Yin,Jun;  Zhu,Hong-Tao;  Zhang,Man;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
浏览  |  Adobe PDF(7092Kb)  |  收藏  |  浏览/下载：74/28  |  提交时间：2022/04/02
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
作者:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
浏览  |  Adobe PDF(8744Kb)  |  收藏  |  浏览/下载：77/35  |  提交时间：2022/04/02
Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell 期刊论文
ONCOGENESIS, 2021, 卷号: 10, 期号: 7, 页码: 49
作者:  He,YingYing;  He,Zhicheng;  Lin,Jian;  Chen,Cheng;  Chen,Yuanzhi;  Liu,Shubai
浏览  |  Adobe PDF(3008Kb)  |  收藏  |  浏览/下载：42/6  |  提交时间：2022/04/02
BINDING-PROTEIN CTBP  TRANSCRIPTIONAL COREPRESSOR  NEGATIVE MODULATION  PROMOTES APOPTOSIS  GENE-EXPRESSION  DAMAGE RESPONSE  PK  OVEREXPRESSION  PHOSPHOPROTEIN  TRANSFORMATION  
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects? 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Puno,Pema Tenzin;  Lau,Clara Bik-San
浏览  |  Adobe PDF(1847Kb)  |  收藏  |  浏览/下载：39/11  |  提交时间：2022/04/02
Breast cancer  Mast cell  Macrophage  Natural products  Herbs  Extracts  TUMOR-ASSOCIATED MACROPHAGES  NF-KAPPA-B  MEDIATED ALLERGIC REACTIONS  PRO-INFLAMMATORY CYTOKINES  ANTIINFLAMMATORY ACTIVITY  ATOPIC-DERMATITIS  UMBROSA ROOT  TNF-ALPHA  IN-VIVO  C-KIT  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
浏览  |  Adobe PDF(3665Kb)  |  收藏  |  浏览/下载：44/6  |  提交时间：2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis 期刊论文
PHYTOMEDICINE, 2020
作者:  Wang Yu-Ling;  Wu Wei;  Su Yong-Nan;  Ai Zhi-Peng;  Mou Han-Chuan;  Wan Luo-Sheng;  Luo Ying;  Qiu Ming-Hua;  Zhang Ji-Hong
浏览  |  Adobe PDF(7972Kb)  |  收藏  |  浏览/下载：103/31  |  提交时间：2021/01/05
Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020
作者:  Zhao, Yun-Li;  Yang, Zi-Feng;  Wu, Bai-Fen;  Shang, Jian-Hua;  Liu, Ya-Ping;  Wang, Xin-Hua;  Luo, Xiao-Dong
浏览  |  Adobe PDF(4071Kb)  |  收藏  |  浏览/下载：125/62  |  提交时间：2021/01/05
Discovery of isopenicin A, a meroterpenoid as a novel inhibitor of tubulin polymerization 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020
作者:  Chen, Lin;  Fan, Dong-Mei;  Tang, Jian-Wei;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Puno, Pema-Tenzin;  Li, Yan
浏览  |  Adobe PDF(1132Kb)  |  收藏  |  浏览/下载：120/40  |  提交时间：2021/01/05