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Synthesis of selective 11 beta-HSD1 inhibitors based on dammarane scaffold 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135, 页码: 324-338
作者:  Shao, Li-Dong;  Bao, Ying;  Shen, Yu;  Su, Jia;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1336Kb)  |  收藏  |  浏览/下载：285/66  |  提交时间：2017/07/31
11 Beta-hsd1 Inhibitor  Hupehenols  Dammarane  Sar  
Synthesis of hupehenols A, B, and E from protopanaxadiol 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 42, 页码: 35792-35803
作者:  Shao, Li-Dong;  Xu, Jun;  Li, Xiao-Nian;  Zhang, Zhi-Jun;  Shi, Xin;  Ren, Jian;  He, Juan;  Zhao, Yu;  Leng, Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1402Kb)  |  收藏  |  浏览/下载：199/57  |  提交时间：2016/08/22
Hupehenols A-E, Selective 11 beta-Hydroxysteroid Dehydrogenase Type 1 (11 beta-HSD1) Inhibitors from Viburnum hupehense 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2015, 卷号: 78, 期号: 2, 页码: 330-334
作者:  Chen, Xuan-Qin;  Shao, Li-Dong;  Pal, Mahesh;  Shen, Yu;  Cheng, Xiao;  Xu, Gang;  Peng, Li-Yan;  Wang, Kou;  Pan, Zheng-Hong;  Li, Ming-Ming;  Leng, Ying;  He, Juan;  Zhao, Qin-Shi;  He,J (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Yunnan,Peoples R China.;  hejuan@mail.kib.ac.cn;  qinshizhao@mail.kib.ac.cn
浏览  |  Adobe PDF(811Kb)  |  收藏  |  浏览/下载：280/81  |  提交时间：2015/06/29
Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11 beta-HSD1 inhibitors: Potential impact in diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 65, 页码: 403-414
作者:  Deng, Xu;  Shen, Yu;  Yang, Jing;  He, Juan;  Zhao, Yu;  Peng, Li-Yan;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1215Kb)  |  收藏  |  浏览/下载：385/148  |  提交时间：2013/10/16
Ent-kaurene Diterpenoids  Structure-activity Relationship Studies  Selective 11 Beta-hsd1 Inhibitors  Urea Derivatives  Diabetes