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Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
Authors:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
Favorite  |  View/Download:13/0  |  Submit date:2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
Authors:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
View  |  Adobe PDF(500Kb)  |  Favorite  |  View/Download:181/70  |  Submit date:2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
Synthesis and anticancer activity of dimeric podophyllotoxin derivatives 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2018, 卷号: 12, 页码: 3393-3406
Authors:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Yang, Dan;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Hu, Jiang-Miao
View  |  Adobe PDF(916Kb)  |  Favorite  |  View/Download:265/56  |  Submit date:2018/11/12
Podophyllotoxin  Dimeric Podophyllotoxin Derivatives  Cuaac Reaction  Perbuty-tylated Glucose  Antitumor  Synthesis  
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
Authors:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
View  |  Adobe PDF(5724Kb)  |  Favorite  |  View/Download:224/8  |  Submit date:2017/12/18
Click Glycosylation for the Synthesis of 1,2,3-Triazole-Linked Picropodophyllotoxin Glycoconjugates and Their Anticancer Activity 期刊论文
CHEMISTRYSELECT, 2017, 卷号: 2, 期号: 18, 页码: 5038-5044
Authors:  Zi, Cheng-Ting;  Yang, Liu;  Gao, Wei;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Hu, Jiang-Miao;  Jiang, Zi-Hua
View  |  Adobe PDF(3775Kb)  |  Favorite  |  View/Download:100/15  |  Submit date:2017/10/23
Anticancer Activity  Cu(i)-catalyzed Click Reaction  Glycoconjugates  Picropodophyllotoxin  Podophyllotoxin  
Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 14, 页码: 3911-3914
Authors:  Wang, Li;  Yang, Jing;  Kong, Ling-Mei;  Deng, Jun;  Xiong, Zijun;  Huang, Jianping;  Luo, Jianping;  Yan, Yijun;  Hu, Yikao;  Li, Xiao-Nian;  Li, Yan;  Zhao, Yong;  Huang, Sheng-Xiong
View  |  Adobe PDF(1338Kb)  |  Favorite  |  View/Download:124/34  |  Submit date:2017/10/23
Protein-kinase-c  Phorbol Esters  Biological Evaluation  Biosynthesis  (+)-phorbol  Analogs  Cancer  Seeds  
Synthesis and Cytotoxic Activity of Novel Hybrid Compounds between Indolo[b]tetrahydrofuran and Imidazolium Salts 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 6, 页码: 1506-1515
Authors:  Liu Zhengfen;  Zhang Chaobo;  Duan Shengzu;  Liu Yang;  Chen Wen;  Li Yan;  Zhang Hongbin;  Yang Xiaodong
View  |  Adobe PDF(1186Kb)  |  Favorite  |  View/Download:53/16  |  Submit date:2017/10/23
Indolo[b]Tetrahydrofuran  Imidazolium Salts  Hybrid Compound  Cytotoxic Activity  
Lanostane-type triterpenoids from Kadsura coccinea 期刊论文
TETRAHEDRON, 2017, 卷号: 73, 期号: 20, 页码: 2931-2937
Authors:  Hu, Zheng-Xi;  Li, Xiao-Nian;  Shi, Yi-Ming;  Wang, Wei-Guang;  Du, Xue;  Li, Yan;  Zhang, Yong-Hui;  Pu, Jian-Xin;  Sun, Han-Dong
View  |  Adobe PDF(860Kb)  |  Favorite  |  View/Download:561/121  |  Submit date:2017/07/10
Kadsura Coccinea  Lanostane-type Triterpenoids  Cytotoxicity  
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
Authors:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
View  |  Adobe PDF(3138Kb)  |  Favorite  |  View/Download:628/99  |  Submit date:2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
Synthesis and cytotoxic activity of novel tetrahydrobenzodifuran-imidazolium salt derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 8, 页码: 1808-1814
Authors:  Zhang, Chao-Bo;  Liu, Yang;  Liu, Zheng-Fen;  Duan, Sheng-Zu;  Li, Min-Yan;  Chen, Wen;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
View  |  Adobe PDF(1192Kb)  |  Favorite  |  View/Download:524/75  |  Submit date:2017/06/30
Tetrahydrobenzodifurans  Imidazolium Salts  Cytotoxic Activity  Cell Cycle  Apoptosis