KIB OpenIR

Browse/Search Results:  1-10 of 110 Help

Selected(0)Clear Items/Page:    Sort:
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 11, 页码: 3576-3589
Authors:  Li, Xue;  Kong, Lingmei;  Yang, Qihong;  Duan, Aizhu;  Ju, Xiaoman;  Cai, Bicheng;  Chen, Lin;  An, Tao;  Li, Yan
Favorite  |  View/Download:4/0  |  Submit date:2020/06/08
small molecule  deubiquitylation (deubiquitination)  Wnt signaling  pharmacology  enzyme inhibitor  ?-catenin  parthenolide  ubiquitination  USP7  Wnt signaling  ubiquitin-specific peptidase 7  colorectal cancer  proteasome system  protein homeostasis  deubiquitinating activity  
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
Authors:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(1740Kb)  |  Favorite  |  View/Download:8/0  |  Submit date:2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Petchiether A attenuates obstructive nephropathy by suppressing TGF-ss/Smad3 and NF-kappa B signalling 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 8, 页码: 5576-5587
Authors:  You, Yong-Ke;  Luo, Qi;  Wu, Wei-Feng;  Zhang, Jiao-Jiao;  Zhu, Hong-Jian;  Lao, Lixing;  Lan, Hui Y.;  Chen, Hai-Yong;  Cheng, Yong-Xian
View  |  Adobe PDF(3491Kb)  |  Favorite  |  View/Download:15/0  |  Submit date:2019/10/14
fibrosis  NF-kappa B  obstructive nephropathy  petchiether A  TGF-ss/Smad3  
Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning 期刊论文
CELL REPORTS, 2019, 卷号: 28, 期号: 2, 页码: 541-+
Authors:  Ma, Pengcheng;  Song, Ning-Ning;  Li, Yongxin;  Zhang, Qiong;  Zhang, Lei;  Zhang, Longlong;  Kong, Qinghua;  Ma, Li;  Yang, Xiangcai;  Ren, Biyu;  Li, Chaocui;  Zhao, Xudong;  Li, Yan;  Xu, Ying;  Gao, Xiang;  Ding, Yu-Qiang;  Mao, Bingyu
View  |  Adobe PDF(5547Kb)  |  Favorite  |  View/Download:78/3  |  Submit date:2019/08/19
Sense Ginsenosides From Ginsengs: Structure-Activity Relationship in Autophagy 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2019, 卷号: 14, 期号: 6, 页码: 10
Authors:  Wu, Tao;  Kwaku, Osafo Raymond;  Li, Hai-Zhou;  Yang, Chong-Ren;  Ge, Long-Jiao;  Xu, Min
View  |  Adobe PDF(1069Kb)  |  Favorite  |  View/Download:19/2  |  Submit date:2019/09/10
ginsengs  ginsenosides  structure-activity relationship  autophagy  
Triterpenes with unusual modifications from the fruiting bodies of the medicinal fungus Irpex lacteus 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 页码: 21-28
Authors:  Tang, Yang;  Zhao, Zhen-Zhu;  Feng, Tao;  Li, Zheng-Hui;  Chen, He-Ping;  Liu, Ji-Kai
View  |  Adobe PDF(681Kb)  |  Favorite  |  View/Download:27/4  |  Submit date:2019/07/29
Irpex lacteus (Fr.) Fr.  Phanerochaetaceae  Eburicane  19(10 -> 5)abeo-eburicane  Lanostane  Triterpenoids  Cytotoxicity  
B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells 期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 18, 页码: 3371-3386
Authors:  Zhou, Hongyu;  Yu, Chunlei;  Kong, Lingmei;  Xu, Xiaoliang;  Yan, Juming;  Li, Yingchao;  An, Tao;  Gong, Liang;  Gong, Yaxiao;  Zhu, Huifang;  Zhang, Hongbin;  Yang, Xiaodong;  Li, Yan
View  |  Adobe PDF(5225Kb)  |  Favorite  |  View/Download:71/3  |  Submit date:2019/06/24
Design, synthesis, and cytotoxic activities of novel hybrids of parthenolide and thiazolidinedione via click chemistry 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
Authors:  Qiu, Jie;  Yuan, Chun-Mao;  Wen, Min;  Li, Ya-Nan;  Chen, Juan;  Jian, Jun-You;  Huang, Lie-Jun;  Gu, Wei;  Li, Yan-Mei;  Hao, Xiao-Jiang
View  |  Adobe PDF(1093Kb)  |  Favorite  |  View/Download:59/3  |  Submit date:2019/07/29
Parthenolide-thiazolidinedione hybrids  click chemistry  cytotoxic activities  
Non-volatile natural products in plant glandular trichomes: chemistry, biological activities and biosynthesis 期刊论文
NATURAL PRODUCT REPORTS, 2019, 卷号: 36, 期号: 4, 页码: 626-665
Authors:  Liu, Yan;  Jing, Shu-Xi;  Luo, Shi-Hong;  Li, Sheng-Hong
View  |  Adobe PDF(5702Kb)  |  Favorite  |  View/Download:73/13  |  Submit date:2019/05/24
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
Authors:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
View  |  Adobe PDF(3189Kb)  |  Favorite  |  View/Download:24/4  |  Submit date:2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer