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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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植物化学与西部植物资... [9]
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孙汉董 [2]
郝小江 [1]
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普诺·白玛丹增 [1]
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专题:植物化学与西部植物资源持续利用国家重点实验室
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A new actinomycin Z analogue with an additional oxygen bridge between chromophore and beta-depsipentapeptide from Streptomyces sp. KIB-H714
期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 2, 页码: 219-225
作者:
Dong, Miao
;
Cao, Pei
;
Ma, Ya-Tuan
;
Luo, Jianying
;
Yan, Yijun
;
Li, Rong-Tao
;
Huang, Sheng-Xiong
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浏览/下载:172/42
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提交时间:2019/07/29
Actinomycin
Streptomyces
cytotoxicity
antibacterial activity
structure elucidation
Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors
期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 33, 页码: 34953-34967
作者:
Liu,Yong-Qiang
;
Wang,Xiao-Lu
;
Cheng,Xin
;
Lu,Yong-Zhi
;
Wang,Gui-Zhen
;
Li,Xin-Chun
;
Zhang,Jian
;
Wen,Zhe-Sheng
;
Huang,Zhi-Liang
;
Gao,Qin-Lei
;
Yang,Li-Na
;
Cheng,Yong-Xian
;
Tao,Sheng-Ce
;
Liu,Jinsong
;
Zhou,Guang-Biao
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浏览/下载:247/63
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提交时间:2016/01/19
Skp1
Lung Cancer
Structure-based High-throughput Virtual Screening
Inhibitors
6-o-angeloylplenolin
The role of targeting kinase activity by natural products in cancer chemoprevention and chemotherapy (Review)
期刊论文
ONCOLOGY REPORTS, 2015, 卷号: 34, 期号: 2, 页码: 547-554
作者:
Luo, Xiangjian
;
Yu, Xinfang
;
Liu, Sufang
;
Deng, Qipan
;
Liu, Xiaolan
;
Peng, Songling
;
Li, Hongde
;
Liu, Jikai
;
Cao, Ya
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浏览/下载:309/161
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提交时间:2015/12/17
Natural Products
Grifolin
Neoalbaconol
Epigallocatechin-3-gallate
Cancer Prevention
A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30
期刊论文
CELL RESEARCH, 2014, 卷号: 24, 期号: 4, 页码: 482-496
作者:
Yue, Wen
;
Chen, Ziheng
;
Liu, Haiyang
;
Yan, Chen
;
Chen, Ming
;
Feng, Du
;
Yan, Chaojun
;
Wu, Hao
;
Du, Lei
;
Wang, Yueying
;
Liu, Jinhua
;
Huang, Xiaohu
;
Xia, Laixin
;
Liu, Lei
;
Wang, Xiaohui
;
Jin, Haijing
;
Wang, Jun
;
Song, Zhiyin
;
Hao, Xiaojiang
;
Chen, Quan
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浏览/下载:585/55
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提交时间:2014/05/16
Mitochondrial Fusion
Mitofusin1/2
Deubiquitinase Usp30
15-oxospiramilactone
Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer
期刊论文
BREAST CANCER RESEARCH, 2014, 卷号: 16, 期号: 4, 页码: 8220-8224
作者:
O'Leary, Patrick C.
;
Terrile, Marta
;
Bajor, Malgorzata
;
Gaj, Pawel
;
Hennessy, Bryan T.
;
Mills, Gordon B.
;
Zagozdzon, Agnieszka
;
O'Connor, Darran P.
;
Brennan, Donal J.
;
Connor, Kate
;
Li, Jane
;
Gonzalez-Angulo, Ana Maria
;
Sun, Han-Dong
;
Pu, Jian-Xin
;
Ponten, Fredrik
;
Uhlen, Mathias
;
Jirstrom, Karin
;
Nowis, Dominika A.
;
Crown, John P.
;
Zagozdzon, Radoslaw
;
Gallagher, William M.
;
Zagozdzon,R (reprint author),UCD Sch Biomol & Biomed Sci,UCD Conway Inst,Canc Biol & Therapeut Lab,Dublin 4,Ireland.
;
radoslaw.zagozdzon@wum.edu.pl
;
william.gallagher@ucd.ie
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浏览/下载:165/56
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提交时间:2015/01/20
Natural-products
Roots
Secretion
Norsesquiterpenoids
Norbisabolane
Pyrimidine
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells
期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:
Zeng, Guang-Zhi
;
Fan, Jun-Ting
;
Xu, Jun-Ju
;
Li, Yan
;
Tan, Ning-Hua
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浏览/下载:217/42
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提交时间:2015/05/14
One Of The Major compOnents Isolated From The Traditional
2-methyl-1
Chinese Medicine Rubia Yunnanensis
3
Exhibited Inhibitory Activity On The proliferatiOn Of Several
6-trihydroxy-9
HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay
10-anthraquinone (Mta)
And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle
Arrest In Human Cervical carcInoma Hela Cells. Further
Mta Was Found To Induce apopTosis Of Hela Cells
Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And
Release Of Cytochrome c Into The Cytosol
Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)
Polymerase And Finally Triggered The Apoptosis. furThermore
The P53/p21/cdc2-cyclin B1 Signaling Was
Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of
Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused
The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of
R. Yunnanensis
a Folk Anti-cancer Herb Used In Yunnan
China.
Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus
期刊论文
NATURE IMMUNOLOGY, 2012, 卷号: 13, 期号: 5, 页码: 474-U73
作者:
Federica Facciotti
;
Gundimeda S Ramanjaneyulu
;
Marco Lepore
;
Sebastiano Sansano
;
Marco Cavallari
;
Magdalena Kistowska
;
Sonja Forss-Petter
;
Guanghui Ni
;
Alessia Colone
;
Amit Singhal
;
Johannes Berger
;
Chengfeng Xia
;
Lucia Mori
;
Gennaro De Libero
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浏览/下载:542/24
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提交时间:2012/06/07
Anticancer Drug
Garcinia Oligantha
Xanthone
Apoptosis
Caspase-3
Derivatives
Activation
Plant-derived small molecule albaconol suppresses LPS-triggered proinflammatory cytokine production and antigen presentation of dendritic cells by impairing NF-kappa B activation
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2008, 卷号: 8, 期号: 8, 页码: 1103-1111
作者:
Liu, Qiuyan
;
Shu, Xiaoli
;
Sun, Anna
;
Sun, Qiaoling
;
Zhang, Chaoxiong
;
An, Huazhang
;
Liu, Jikai
;
Cao, Xuetao
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浏览/下载:277/75
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提交时间:2011/12/19
Dendritic Cell
Immunosuppression
Inflammation
Cytokines
Nf-kappa b
Novel mechanism of inhibition of nuclear factor-kappa B DNA-binding activity by diterpenoids isolated from Isodon rubescens
期刊论文
MOLECULAR PHARMACOLOGY, 2005, 卷号: 68, 期号: 2, 页码: 286-297
作者:
Leung, CH
;
Grill, SP
;
Lam, W
;
Han, QB
;
Sun, HD
;
Cheng, YC
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浏览/下载:99/35
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提交时间:2015/09/23