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The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载:257/1  |  提交时间:2017/07/24
The dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2-dependent and -independent fever while 4-AA only blocks PGE2-dependent fever1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
作者:  David do C. Malvar;  Fernando A. Aguiar;  Artur de L. L. Vaz;  Débora C. R. Assis;  Miriam C. C. de Melo;  Valquíria A. P. Jabor;  Evanguedes Kalapothakis;  Sérgio H. Ferreira;  Giuliano C. Clososki;  Glória E. P. de Souza
Adobe PDF(2243Kb)  |  收藏  |  浏览/下载:282/1  |  提交时间:2017/07/24
Dipyrone  Dipyrone Metabolites  Fever  Hypothermia  Lps  Tityus Serrulatus Venom  
Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins 期刊论文
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
作者:  Pauline Macheboeuf;  Delphine S Fischer;  Tom Brown Jr;  Astrid Zervosen;  Andre´Luxen;  Bernard Joris;  Andrea Dessen;  Christopher J Schofield
Adobe PDF(425Kb)  |  收藏  |  浏览/下载:79/1  |  提交时间:2017/07/21
Increased Catalytic Efficiency following Gene Fusion of Bifunctional MethionineSulfoxide Reductase Enzymes from Shewanella oneidensis 期刊论文
Biochemistry, 3111, 页码: 1—9
作者:  C.B. Li;  D.M. Zhang;  S. Ge;  D.Y. Hong
Adobe PDF(436Kb)  |  收藏  |  浏览/下载:99/1  |  提交时间:2017/07/19
The pharmacokinetics of anthocyanins and their metabolites in humans 期刊论文
出版物, 3111, 期号: 0, 页码: 1-37
作者:  R M de Ferrars;  C Czank;  Q Zhang;  N P Botting;  P A Kroon;  A Cassidy;  C D Kay
Adobe PDF(1873Kb)  |  收藏  |  浏览/下载:114/1  |  提交时间:2017/07/24
Anthocyanins  Metabolites  Hippuric Acid  Ferulic Acid  Vanillic Acid  
Design, Synthesis, and Biological Evaluation of Novel Benzofuran Derivatives Bearing N-Aryl Piperazine Moiety 期刊论文
Molecules, 2016, 卷号: 21, 页码: 1684
作者:  Yulu Ma
Adobe PDF(907Kb)  |  收藏  |  浏览/下载:45/0  |  提交时间:2017/08/21
The re‑emergence of natural products for drug discovery in the genomics era 期刊论文
Nature Reviews Drug Discovery, 2015, 页码: nrd4510
作者:  Alan L. Harvey
Adobe PDF(540Kb)  |  收藏  |  浏览/下载:68/0  |  提交时间:2017/08/22
Antichlamydial Sterol from the Red Sea Sponge Callyspongia aff. implexa 期刊论文
planta medica, 2015, 页码: 1
作者:  Usama Ramadan Abdelmohsen
Adobe PDF(196Kb)  |  收藏  |  浏览/下载:42/0  |  提交时间:2017/08/23
Metal-catalysed azidation of tertiary C–H bonds suitable for late-stage functionalization 期刊论文
N AT U R E, 2015, 页码: 600
作者:  Ankit Sharma;John F. Hartwig
Adobe PDF(512Kb)  |  收藏  |  浏览/下载:36/0  |  提交时间:2017/08/17
Phytochemical Content, Health Benefits, and Toxicology of Common Edible Flowers: A Review (2000–2015) 期刊论文
Critical Reviews in Food Science and Nutrition, 2015, 页码: 1
作者:  Baiyi Lu
Adobe PDF(928Kb)  |  收藏  |  浏览/下载:70/0  |  提交时间:2017/08/17