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昆明植物所硕博研究生... [1]

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2010 [1]

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KIB OpenIR

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语种：中文资助项目：This thesis contains three chapters. The first chapter elaborated the studies on the chemical constituents of Cimicifuga foetida collected in Dali, Yunnan Province. The second chapter elaborated the studies on the chemical constituents of C. heracleifolia collected in Qingyuan, Liaoning Province. a total of 33 compounds were isolated and identified from the above two genus Cimicifuga plants, involving triterpenoid glycosides, chromoes, phenylpropanoids, of which 5 are new and 25 are triterpenoid glycosides. The third chapter introduced the progress in studies on the chemical constituents and bioactivities of genus Cimicifuga plants.Chapter Ⅰ: Studies on the chemical constituents of C. foetida collected in Dali, Yunnan Province. In order to seek for the active compounds, we have studied the chemical constituents of C. foetida rhizomes collected in Dali, Yunnan Province. 23 compounds were isolated and elucidated, including 17 triterpenoid glycosides, 2 chromones, 1 cerebroside, 2 phenylpropanoids, and 1 steroide, of which 5 are new, involving triterpenoid glycosides.Chapter Ⅱ: Studies on the constituents of C. heracleifolia collected in Liaoning province. In order to promote efficient use of resources, we have studied the chemical constituents of aerial parts of C. heracleifolia collected in Qingyuan, Liaoning province. 10 compounds were isolated and elucidated , including 8 triterpenoid glycosides, and 2 chromone.Chapter Ⅲ: Progress in studies on the chemical constituents and bioactivities of C. genus plants. In recent decades, there were a thorough research on the chemical constituents and bioactivities of genus C. plants at home and abroad. There were more than 170 compouds were isolated from genus C. plants, involving triterpenoids, triterpenoid glycosides, chromone, phenylpropanoids, alkaloids, and other types of compounds. 9,19-cycleartane type triterpenoids and triterpenoid glycosides are the major chemical constituents of the genus C. plants, while triterpenoidsare also the main active components which show many pharmacological activities, including anti-tumor activity, anti-complement activity, anti-nucleoside transport inhibition, antiviral activity, lipid-lowering effect, detoxification, and anti-osteoporotic activity.

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