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Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating [4+2] cycloaddition and target differentiation of enantiomers 期刊论文
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 4
作者:  He, Tao-Bin;  Yan, Bing-Chao;  Zhou, Yuan-Fei;  Sang, Yue-Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Wang, Chu;  Xue, Xiao-Song;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(3322Kb)  |  收藏  |  浏览/下载：87/33  |  提交时间：2024/05/09
DIELS-ALDER REACTION  BIOMIMETIC SYNTHESES  EFFICIENT ACCESS  DEHYDROGENATION  CYCLOHEXANONES  BIOSYNTHESIS  CONVERSION  OXIDATION  DYNAMICS  PHENOLS  
Cyclobutane-Containing Meroditerpenoids, (+)-Isoscopariusins B and C: Structure Elucidation and Biomimetic Synthesis 期刊论文
ORGANIC LETTERS, 2023, 卷号: 25, 期号: 17, 页码: 2981-2985
作者:  Li,Ming-Xiang;  Yan,Bing-Chao;  Zhou,Min;  Li,Xing-Ren;  Li,Xiao-nian;  He,Shi-Jun;  Sun,Han-Dong;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(1928Kb)  |  收藏  |  浏览/下载：15/5  |  提交时间：2024/07/10
2+2 PHOTOCYCLOADDITION REACTIONS  VISIBLE-LIGHT PHOTOCATALYSIS  LEWIS-ACID CATALYSIS  CYCLOADDITIONS  DERIVATIVES  
Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
作者:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(7289Kb)  |  收藏  |  浏览/下载：35/10  |  提交时间：2024/07/10
Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Synthesis of nigranoic acid and manwuweizic acid derivatives as HDAC inhibitors and anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 109, 页码: 104728
作者:  Ni,Dong-Xuan;  Wang,Qi;  Li,Yi-Ming;  Cui,Yi-Man;  Shen,Tian-Ze;  Li,Xiao-Li;  Sun,Han-Dong;  Zhang,Xing-Jie;  Zhang,Ruihan;  Xiao,Wei-Lie
收藏  |  浏览/下载：77/0  |  提交时间：2022/04/02
Natural products modification  HDAC inhibition  Inflammasome  Triterpenoid  SCHISANDRA-PROPINQUA  TRITERPENOIDS  MECHANISM  INJURY  
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 11, 页码: 7404-7421
作者:  Zhou,Zongyuan;  Li,Yiming;  Ma,Xiaofang;  Cao,Biyun;  Peng,Ting;  Sheng,Yuwen;  Peng,Huipan;  Li,Runze;  Cao,Yu;  Xi,Ruiying;  Li,Fu;  Wang,Mengru;  Sun,Handong;  Zhang,Guolin;  Zhang,Hongbin;  Hu,Kaifeng;  Xiao,Weilie;  Wang,Fei
收藏  |  浏览/下载：110/0  |  提交时间：2022/04/02
GOMISIN-A  DIBENZOCYCLOOCTADIENE LIGNANS  SCHISANDRA-CHINENSIS  MASS-SPECTROMETRY  MIRNA EXPRESSION  DOWN-REGULATION  NONCODING RNA  MICRORNA  LIVER  DICER  
Spiro ent-Clerodane Dimers: Discovery and Green Approaches for a Scalable Biomimetic Synthesis 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 15, 页码: 5647-5651
作者:  Li,Xing-Ren;  Yan,Bing-Chao;  Hu,Kun;  He,Shijun;  Sun,Han-Dong;  Zuo,Jianping;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(1474Kb)  |  收藏  |  浏览/下载：108/27  |  提交时间：2022/04/02
DIELS-ALDER REACTIONS  SENSITIZED PHOTOOXYGENATION  NATURAL-PRODUCTS  ACID  DITERPENOIDS  
(-)-Isoscopariusin A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 23, 页码: 12859-12867
作者:  Yan,Bing-Chao;  Zhou,Min;  Li,Jian;  Li,Xiao-Nian;  He,Shi-Jun;  Zuo,Jian-Ping;  Sun,Han-Dong;  Li,Ang;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(1930Kb)  |  收藏  |  浏览/下载：129/29  |  提交时间：2022/04/02
bioactivity  cyclobutane  natural products  scalable synthesis  structure elucidation  
Pestaloamides A and B, two spiro-heterocyclic alkaloid epimers from the plant endophytic fungus Pestalotiopsis sp. HS30 期刊论文
SCIENCE CHINA-CHEMISTRY, 2020
作者:  Su, Xiao-Zheng;  Zhu, Yi-Ying;  Tang, Jian-Wei;  Hu, Kun;  Li, Xiao-Nian;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
Adobe PDF(858Kb)  |  收藏  |  浏览/下载：190/64  |  提交时间：2021/01/05
Elucidation of the Structure of Pseudorubriflordilactone B by Chemical Synthesis 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020
作者:  Yang, Peng;  Li, Jian;  Sun, Li;  Yao, Ming;  Zhang, Xiang;  Xiao, Wei-Lie;  Wang, Jian-Hua;  Tian, Ping;  Sun, Han-Dong;  Puno, Pema-Tenzin;  Li, Ang
Adobe PDF(2437Kb)  |  收藏  |  浏览/下载：214/54  |  提交时间：2021/01/05
4,5-Seco-18-nor-ent-clerodanoids and their derivatives: Structure elucidation, synthesis and resistant reversal activities against fluconazole-resistance Candida albicans 期刊论文
TETRAHEDRON, 2020
作者:  Jiang, Xue-Chun;  Yan, Bing-Chao;  Li, Xing-Ren;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
Adobe PDF(920Kb)  |  收藏  |  浏览/下载：155/47  |  提交时间：2021/01/05