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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
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Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
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Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Pepluenone, a new pepluane-type diterpenoid with inhibitory activity on the release of NO from the whole plant of Euphorbia peplus L. 期刊论文
TETRAHEDRON LETTERS, 2023, 卷号: 123, 页码: 154550
作者:  Huang,Jian-Yi;  Yang,Ying;  Liang,Hong;  Pu,Xue-Xue;  Li,Ying-Yao;  Cai,Min;  Guo,Feng;  Liu,Lin;  Cao,Ming-Ming;  Yan,Ying;  Cheng,Yuanyuan;  Di,Ying-Tong;  Hao,Xiao-Jiang
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Anti-inflammatory  Pepluane  Diterpenoid  Euphorbia peplus L  Chemical transformation  DISCOVERY  PARALIANE  INSIGHTS  PROFILE  LATEX  
Chemical Constituents of Primulina eburnea (Gesneriaceae) and Their Cytotoxic Activities 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
作者:  Yang,Li-Yuan;  Yi,Ping;  Chen,Jun-Lei;  Li,Yu-Huan;  Qiu,Jue-Lin;  Wang,Zhao-Yang;  Fu,Mao;  Yuan,Chun-Mao;  Huang,Lie-Jun;  Hao,Xiao-Jiang;  Gu,Wei
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Primulina eburnea  triterpenes  flavonoids  phenylethanoid glycosides  cytotoxic activity  GLUCOSIDES  LEAVES  CELL  
Does competitive asymmetry confer polyploid advantage under changing environments? 期刊论文
JOURNAL OF ECOLOGY, 2023
作者:  Guo,Wen;  Wei,Na;  Hao,Guang-You;  Yang,Shi-Jian;  Zhu,Zhi-Yong;  Yang,Yong-Ping;  Duan,Yuan-Wen
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competition coefficient  competitive asymmetry  drought  functional traits  gas exchange  polyploidy  stress gradient hypothesis  water use efficiency  WATER-USE EFFICIENCY  BRACHYPODIUM-DISTACHYON  NICHE DIFFERENTIATION  PLANT INTERACTIONS  TRADE-OFFS  ESTABLISHMENT  EVOLUTIONARY  DISTURBANCE  ABILITY  PHOTOSYNTHESIS  
UPLC-Q-Orbitrap-MS/MS-Guided Isolation of Bioactive Withanolides from the Fruits of Physalis angulata 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 44, 页码: 16581-16592
作者:  Wang,Peng;  Yang,Xiao-Meng;  Hu,Zhan-Xing;  Li,Ya-Nan;  Yang,Jue;  Hao,Xiao-Jiang;  Yuan,Chun-Mao;  Yi,Ping
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Physalis angulata  rare withanolidederivatives  isolation and identification  anticancer  anti-inflammatory activity  CYTOTOXIC WITHANOLIDES  CONSTITUENTS  PLANTS  L.  
Artemeriopolides A-D, two types of sesquiterpenoid dimers with rare carbon skeletons from Artemisia eriopoda and their antihepatoma cytotoxicity 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 11, 页码: 2635-2641
作者:  He,Xiao-Feng;  Li,Qi-Hao;  Li,Tian-Ze;  Ma,Yun-Bao;  Dong,Wei;  Yang,Ke-Xin;  Geng,Chang-An;  Zhang,Hao-Wei;  Wang,Yuan;  Chen,Ji-Jun
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A flavonolignan, flavonoids and alkylamides from the fruits of Zanthoxylum Motuoense Huang 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2023, 卷号: 109, 页码: 104659
作者:  Wei,Yinghuan;  Chen,Junlei;  Qiu,Juelin;  Wang,Zhaoyang;  Li,Huanyang;  Yang,Jue;  Huang,Liejun;  Yuan,Chunmao;  Hao,Xiaojiang;  Gu,Wei
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Zanthoxylum motuoense Huang  Flavonolignan  Alkylamides  Neuroprotective activity  Chemotaxonomy  ALIPHATIC ACID-AMIDES  
Bioassay-guided isolation of α-Glucosidase inhibitory constituents from Hypericum sampsonii 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 6, 页码: 443-453
作者:  Tao,Linlan;  Xu,Shuangyu;  Zhang,Zizhen;  Li,Yanan;  Yang,Jue;  Gu,Wei;  Yi,Ping;  Hao,Xiaojiang;  Yuan,Chunmao
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Hypericum sampsonii  Chemical constituents  Structure elucidation  alpha-Glucosidase  Molecular docking  POLYCYCLIC POLYPRENYLATED ACYLPHLOROGLUCINOLS  POTENT INHIBITORS  SPECTROSCOPY  DERIVATIVES  CHEMISTRY  AMYLASE  ROOTS  
Discovery of diverse sesquiterpenoids from Magnolia grandiflora with cytotoxic activities by inducing cell apoptosis 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 106707
作者:  Xu,Shuangyu;  Tang,Yunyan;  Li,Yanan;  Yang,Jue;  Gu,Wei;  Hao,Xiaojiang;  Yuan,Chunmao
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Magnolia grandiflora  Sesquiterpenoids  Isolation and structural modification  Cytotoxic activity  Apoptosis  LACTONES  DERIVATIVES  LEAVES  AGENTS