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Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway 期刊论文
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
作者:  Geng,Chang-An;  Chen,Feng-Yang;  Zheng,Jing-Bin;  Liao,Ping;  Li,Tian-Ze;  Zhang,Xue-Mei;  Chen,Xin;  Chen,Ji-Jun
浏览  |  Adobe PDF(5670Kb)  |  收藏  |  浏览/下载：11/3  |  提交时间：2024/07/17
Rubiginosin B (RGB)  CD4(+)Foxp3(+) regulatory T cells (Tregs)  Calcineurin  Nuclear factor of activated T cells (NFAT)  Tumor microenvironment  Rhododendron brachypodum  REGULATORY T-CELLS  RHODODENDRON  IMMUNOSUPPRESSION  DERIVATIVES  INDUCTION  EXPANSION  RAPAMYCIN  
Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift 期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
作者:  Zhang,Xin-Tian;  Hu,Jing;  Su,Li-Hua;  Geng,Chang-An;  Chen,Ji-Jun
浏览  |  Adobe PDF(6313Kb)  |  收藏  |  浏览/下载：147/40  |  提交时间：2022/04/02
Artemisia atrovirens  Cervical cancer  ERK pathway  Cell metabolism  ALKALINE-PHOSPHATASE  SIGNALING PATHWAY  DIFFERENTIATION  APOPTOSIS  ERK  MECHANISMS  
Tsaokols A and B, unusual flavanol-monoterpenoid hybrids as alpha-glucosidase inhibitors from Amomum tsao-ko 期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 3, 页码: 1202-1205
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(688Kb)  |  收藏  |  浏览/下载：111/35  |  提交时间：2022/04/02
Amomum tsao-ko  Zingiberaceae  Flavanol-monoterpenoid hybrids  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  CREVOST  
ent-Labdane and ent-kaurane diterpenoids from Chelonopsis odontochila with alpha-glucosidase inhibitory activity 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Deng, Zhen-Tao;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(3607Kb)  |  收藏  |  浏览/下载：141/42  |  提交时间：2021/01/05
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 期号: 0, 页码: 381-393
作者:  Yang, Tong-Hua;  Ma, Yun-Bao;  Geng, Chang-An;  Yan, De-Xiu;  Huang, Xiao-Yan;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2088Kb)  |  收藏  |  浏览/下载：244/77  |  提交时间：2018/10/04
Depression  Magnolol Derivatives  Mt1/2 Receptors  Metabolites  Monoamine Neurotransmitter  
Chemical and biological comparison of different sections of Uncaria rhynchophylla (Gou-Teng) 期刊论文
EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2017, 卷号: 23, 期号: 1, 页码: 11-21
作者:  Zhang, Jian-Gang;  Geng, Chang-An;  Huang, Xiao-Yan;  Chen, Xing-Long;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(521Kb)  |  收藏  |  浏览/下载：379/76  |  提交时间：2017/06/30
Uncaria Rhynchophylla  Gou Teng  Lc-ms Analysis  Chemical Profiles  Mt1/2 And 5-ht1a/2c Receptors  Indole Alkaloids  
Catalytic Asymmetric Total Synthesis of (+)- and (-)-Paeoveitol via a Hetero-Diels-Alder Reaction 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 3, 页码: 429-431
作者:  Li,Tian-Ze;  Geng,Chang-An;  Yin,Xiu-Juan;  Yang,Tong-Hua;  Chen,Xing-Long;  Huang,Xiao-Yan;  Ma,Yun-Bao;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(553Kb)  |  收藏  |  浏览/下载：191/61  |  提交时间：2017/10/23
Ortho-quinone Methides  Paeonia-veitchii  Natural-products  Paeoveitol  
Bioactivity-guided isolation of anti-hepatitis B virus active sesquiterpenoids from the traditional Chinese medicine: Rhizomes of Cyperus rotundus 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2015, 卷号: 171, 期号: 1, 页码: 131-140
作者:  Xu, Hong-Bo;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Wang, Hao;  Zhao, Yong;  Yang, Tong-Hua;  Chen, Xing-Long;  Yang, Cai-Yan;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1303Kb)  |  收藏  |  浏览/下载：263/86  |  提交时间：2016/01/19
Cyperus Rotundus  Lc-ms-it-tof  Sesquiterpenoids  Anti-hbv Activity  
Isolation and anti-hepatitis B virus activity of dibenzocyclooctadiene lignans from the fruits of Schisandra chinensis 期刊论文
PHYTOCHEMISTRY, 2015, 卷号: 116, 页码: 253-261
作者:  Xue, Yongbo;  Li, Xifeng;  Du, Xue;  Li, Xiaonian;  Wang, Weiguang;  Yang, Jianhong;  Chen, Jijun;  Pu, Jianxin;  Sun, Handong
浏览  |  Adobe PDF(650Kb)  |  收藏  |  浏览/下载：304/119  |  提交时间：2015/12/17
Schisandra Chinensis  Schisandraceae  Dibenzocyclooctadiene Lignans  Hepatitis b Virus  6  7-seco-homolignan  
Lignans from the Fruits of Melia toosendan and Their Agonistic Activities on Melatonin Receptor MT1 期刊论文
PLANTA MEDICA, 2015, 卷号: 81, 期号: 10, 页码: 847-854
作者:  Wang, Hao;  Geng, Chang-An;  Xu, Hong-Bo;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Yang, Cai-Yan;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(244Kb)  |  收藏  |  浏览/下载：275/99  |  提交时间：2015/12/17
Melia Toosendan  Meliaceae  Lignans  Mt1 Receptor  Agonistic Activity