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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
作者:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  收藏  |  浏览/下载：313/1  |  提交时间：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：317/1  |  提交时间：2017/07/24
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
作者:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  收藏  |  浏览/下载：346/1  |  提交时间：2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα 期刊论文
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2023, 卷号: 21, 期号: 5, 页码: 1274-1288
作者:  Shen,Chuanbin;  Mackeigan,Daniel T.;  Shoara,Aron A.;  Xu,Runjia;  Bhoria,Preeti;  Karakas,Danielle;  Ma,Wenjing;  Cerenzia,Eric;  Chen,ZiYan;  Hoard,Brock;  Lin,Lisha;  Lei,Xi;  Zhu,Guangheng;  Chen,Pingguo;  Johnson,Philip E.;  Ni,Heyu
浏览  |  Adobe PDF(4055Kb)  |  收藏  |  浏览/下载：21/5  |  提交时间：2024/07/22
fucoidan  glycoprotein Ib  platelet  thrombosis  von Willebrand factor  VON-WILLEBRAND-FACTOR  PLATELET GLYCOPROTEIN IB  MOLECULAR-WEIGHT FUCOIDAN  ARTERIAL THROMBOSIS  IX  AGGREGATION  RECEPTOR  ACTIVATION  FIBRINOGEN  INTEGRIN  
Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis 期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 卷号: 43, 期号: 2, 页码: 253-266
作者:  Li,Sujuan;  Wang,Weili;  Lin,Lisha;  Yang,Lian;  Cai,Ying;  Yang,Xingzhi;  Zhang,Taocui;  Xiao,Chuang;  Yan,Hui;  Gao,Na;  Zhao,Jinhua
浏览  |  Adobe PDF(2610Kb)  |  收藏  |  浏览/下载：56/15  |  提交时间：2024/05/09
oligosaccharide  platelet activation  receptor  protease-activated  thrombin thrombosis  ANTIPLATELET THERAPIES  ALLOSTERIC LINKAGE  TISSUE FACTOR  PROTEASE  VORAPAXAR  MECHANISM  REVEALS  SITE  
Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118290
作者:  Li,Shanni;  Zhong,Wei;  Pan,Ying;  Lin,Lisha;  Cai,Ying;  Mao,Hui;  Zhang,Taocui;  Li,Sujuan;  Chen,Ru;  Zhou,Lutan;  Wang,Weili;  Cui,Qinghua;  Yin,Ronghua;  Huang,Shengxiong;  Zhao,Jinhua
浏览  |  Adobe PDF(2581Kb)  |  收藏  |  浏览/下载：239/31  |  提交时间：2022/04/02
Disaccharide branch  Fucosylated glycosaminoglycan  Holothuria nobilis  Oligosaccharide  Anticoagulant  INTRINSIC TENASE COMPLEX  CHONDROITIN SULFATE  ACAUDINA-MOLPADIOIDEA  FACTOR XASE  HEPARIN  DEPOLYMERIZATION  OLIGOSACCHARIDES  POLYSACCHARIDES  DERIVATIVES  
Novel Signature Genes and Pathways Identified for Human Left Ventricle Cardiomyopathies Rise from different Etiologies 期刊论文
Journal of Biomedical Research and Reviews, 2021
作者:  Jiao Tian;  Zheng Yuan Wu;  Ying Ying He;  Shubai Liu
浏览  |  Adobe PDF(1819Kb)  |  收藏  |  浏览/下载：72/27  |  提交时间：2023/09/08
Neolignans and Norlignans from Insect Medicine Polyphaga plancyi and Their Biological Activities 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 1, 页码: 51-62
作者:  Zhu,Hong-Jie;  Xu,Te;  Yan,Yong-Ming;  Tu,Zheng-Chao;  Cheng,Yong-Xian
浏览  |  Adobe PDF(1659Kb)  |  收藏  |  浏览/下载：142/32  |  提交时间：2022/04/02
The Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 9, 页码: 487
作者:  Lin,Lisha;  Li,Sujuan;  Gao,Na;  Wang,Weili;  Zhang,Taocui;  Yang,Lian;  Yang,Xingzhi;  Luo,Dan;  Ji,Xu;  Zhao,Jinhua
浏览  |  Adobe PDF(2854Kb)  |  收藏  |  浏览/下载：149/28  |  提交时间：2022/04/02
fucosylated glycosaminoglycan  anticoagulant  platelet aggregation  contact activation  hypotension  pulmonary embolism  CHONDROITIN SULFATE  CONTACT SYSTEM  COMPLEMENT  COAGULATION  ACTIVATION  ACCUMULATION  INVOLVEMENT  DERIVATIVES  KALLIKREIN  THROMBOSIS  
High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on alpha(IIb)beta(3) and platelet secretion 期刊论文
PLATELETS, 2021, 卷号: 32, 期号: 7, 页码: 975-983
作者:  Lin,Lisha;  Yang,Lian;  Chen,Jun;  Zhou,Lutan;  Li,Sujuan;  Gao,Na;  Zhao,Jinhua
浏览  |  Adobe PDF(3733Kb)  |  收藏  |  浏览/下载：95/23  |  提交时间：2022/04/02
Aggregation  fucosylated glycosaminoglycan  human platelets  secretion  alpha(IIb beta 3)  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  INTEGRIN ALPHA(IIB)BETA(3)  ACTIVATION  AGGLUTINATION  RECEPTOR  ADP  INHIBITION  GENERATION  MECHANISM