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New Phenolic Dimers from Plant Paeonia suffruticosa and Their Cytotoxicity and NO Production Inhibition 期刊论文
Molecules, 2023
作者:  Qianqian Meng;  Shunyao Tong;  Yuqing Zhao;  Xingrong Peng;  Zhenghui Li;  Tao Feng;  Jikai Liu
Adobe PDF(1414Kb)  |  收藏  |  浏览/下载：483/78  |  提交时间：2023/10/07
High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：36/8  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
浏览  |  Adobe PDF(11543Kb)  |  收藏  |  浏览/下载：29/11  |  提交时间：2024/07/17
Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway 期刊论文
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
作者:  Geng,Chang-An;  Chen,Feng-Yang;  Zheng,Jing-Bin;  Liao,Ping;  Li,Tian-Ze;  Zhang,Xue-Mei;  Chen,Xin;  Chen,Ji-Jun
浏览  |  Adobe PDF(5670Kb)  |  收藏  |  浏览/下载：28/10  |  提交时间：2024/07/17
Rubiginosin B (RGB)  CD4(+)Foxp3(+) regulatory T cells (Tregs)  Calcineurin  Nuclear factor of activated T cells (NFAT)  Tumor microenvironment  Rhododendron brachypodum  REGULATORY T-CELLS  RHODODENDRON  IMMUNOSUPPRESSION  DERIVATIVES  INDUCTION  EXPANSION  RAPAMYCIN  
Pharmacological investigation of indole alkaloids from Alstonia scholaris against chronic glomerulonephritis 期刊论文
PHYTOMEDICINE, 2023, 卷号: 118, 页码: 154958
作者:  Guo,Rui;  Shang,Jian-Hua;  Ye,Rui-Han;  Zhao,Yun-Li;  Luo,Xiao-Dong
浏览  |  Adobe PDF(15381Kb)  |  收藏  |  浏览/下载：22/7  |  提交时间：2024/07/17
Alstonia scholaris  Indole alkaloids  Chronic glomerulonephritis  Network pharmacology  PI3K-AkT pathway  LEAVES  IDENTIFICATION  CONSTITUENTS  EXTRACT  MODELS  POTENT  
Bioactive triterpenoids from the traditional Chinese medicine Swertia mileensis 期刊论文
PHYTOCHEMISTRY LETTERS, 2023, 卷号: 55, 页码: 1-5
作者:  Yuan,Xin;  Yan,Qin;  Hu,Hong;  He,Xiao-Ping;  Wang,Li-Xia;  Liu,Yan-Chun;  Liu,Yan;  Guo,Kai;  Li,Sheng-Hong
浏览  |  Adobe PDF(592Kb)  |  收藏  |  浏览/下载：23/9  |  提交时间：2024/07/22
Swertia mileensis  Gentianaceae  Triterpenoids  Anti-inflammatory activity  Cytotoxicity  
Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 210, 页码: 113642
作者:  Liu,Jie;  Yan,Qin;  Wang,Li-Xia;  He,Xiao-Ping;  Hu,Hong;  Liu,Yan-Chun;  Li,Dan;  Liu,Yan;  Guo,Kai;  Li,Sheng-Hong
浏览  |  Adobe PDF(643Kb)  |  收藏  |  浏览/下载：25/7  |  提交时间：2024/07/22
Swertia pseudochinensis Hara  Gentianaceae  Secoiridoids  Anti-inflammatory activity  NATURALLY-OCCURRING IRIDOIDS  CHEMICAL-CONSTITUENTS  PART  BIOTRANSFORMATION  GENTIOPICROSIDE  BIOSYNTHESIS  GLUCOSIDES  
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载：28/6  |  提交时间：2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum 期刊论文
FITOTERAPIA, 2023, 卷号: 165, 页码: 105402
作者:  Guo,Kai;  Ren,Xue;  Zhou,Ting-Ting;  Li,Tao;  Liu,Yan-Chun;  Tao,Yang;  Hu,Hong;  Li,Dan;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(1128Kb)  |  收藏  |  浏览/下载：28/10  |  提交时间：2024/07/25
Lomatogonium carinthiacum  Gentianaceae  Monoterpenoids  Monoterpenoid alkaloids  Sesquiterpenoids  Immunosuppressive activity  STRUCTURAL ELUCIDATION  GLYCOSIDES  SECOIRIDOIDS  GLUCOSIDE  PART  
Clerodane diterpenoids from the Uygur medicine Salvia deserta with immunosuppressive activity 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113823
作者:  Ren,Xue;  Yuan,Xin;  Jiao,Shan-Shan;  He,Xiao-Ping;  Hu,Hong;  Kang,Juan-Juan;  Luo,Shi-Hong;  Liu,Yan;  Guo,Kai;  Li,Sheng-Hong
浏览  |  Adobe PDF(3695Kb)  |  收藏  |  浏览/下载：21/10  |  提交时间：2024/07/25
Salvia deserta  Lamiaceae  Clerodane diterpenoids  Chemical constituents  ROOTS