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Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis 期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 卷号: 43, 期号: 2, 页码: 253-266
作者:  Li,Sujuan;  Wang,Weili;  Lin,Lisha;  Yang,Lian;  Cai,Ying;  Yang,Xingzhi;  Zhang,Taocui;  Xiao,Chuang;  Yan,Hui;  Gao,Na;  Zhao,Jinhua
浏览  |  Adobe PDF(2610Kb)  |  收藏  |  浏览/下载：56/15  |  提交时间：2024/05/09
oligosaccharide  platelet activation  receptor  protease-activated  thrombin thrombosis  ANTIPLATELET THERAPIES  ALLOSTERIC LINKAGE  TISSUE FACTOR  PROTEASE  VORAPAXAR  MECHANISM  REVEALS  SITE  
Structural Characterization and Anticoagulant Activities of a Keratan Sulfate-like Polysaccharide from the Sea Cucumber Holothuria fuscopunctata 期刊论文
MARINE DRUGS, 2023, 卷号: 21, 期号: 12, 页码: 632
作者:  Chen,Ru;  Wang,Weili;  Yin,Ronghua;  Pan,Ying;  Xu,Chen;  Gao,Na;  Luo,Xiaodong;  Zhao,Jinhua;  Reyes,Fernando
浏览  |  Adobe PDF(6775Kb)  |  收藏  |  浏览/下载：58/20  |  提交时间：2024/05/09
aminoglycan  structural features  keratan sulfate  depolymerization  oligosaccharides  anticoagulant activity  INTRINSIC-FACTOR XASE  GLYCOSAMINOGLYCAN  OLIGOSACCHARIDES  DEPOLYMERIZATION  ELUCIDATION  DERIVATIVES  HEPARIN  
Structural characterization of oligosaccharides from free radical depolymerized fucosylated glycosaminoglycan and suggested mechanism of depolymerization 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 270, 页码: 118368
作者:  Chen,Ru;  Yin,Ronghua;  Li,Shanni;  Pan,Ying;  Mao,Hui;  Cai,Ying;  Lin,Lisha;  Wang,Weili;  Zhang,Taocui;  Zhou,Lutan;  Gao,Na;  Luo,Xiaodong;  Zhao,Jinhua
浏览  |  Adobe PDF(3356Kb)  |  收藏  |  浏览/下载：119/31  |  提交时间：2022/04/02
Fucosylated glycosaminoglycan  Free radical depolymerization  Chemical structure  Oligosaccharide  NMR  INTRINSIC TENASE COMPLEX  ANTICOAGULANT ACTIVITIES  SEA-CUCUMBER  CHONDROITIN SULFATE  PHYSICOCHEMICAL CHARACTERISTICS  FACTOR XASE  POLYSACCHARIDES  DERIVATIVES  HEPARIN  
Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 166, 页码: 105527
作者:  Zhou,Lutan;  Yin,Ronghua;  Gao,Na;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Ren,Lin;  Yang,Lian;  Zuo,Zhili;  Zhang,Hongbin;  Zhao,Jinhua
浏览  |  Adobe PDF(8336Kb)  |  收藏  |  浏览/下载：175/20  |  提交时间：2022/04/02
Oligosaccharides  Heparanase  Angiogenesis  Metastasis  FIBROBLAST-GROWTH-FACTOR  TUMOR-GROWTH  SULFATE PROTEOGLYCANS  MAMMALIAN HEPARANASE  COMBINATION  MECHANISMS  DISCOVERY  BINDING  TARGET  PI-88  
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives 期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
作者:  Yin,Ronghua;  Zhou,Lutan;  Gao,Na;  Lin,Lisha;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Zuo,Zhili;  Hu,Kaifeng;  Huang,Shengxiong;  Liu,Jikai;  Zhao,Jinhua
浏览  |  Adobe PDF(4401Kb)  |  收藏  |  浏览/下载：136/30  |  提交时间：2022/04/02
FUCOSYLATED CHONDROITIN SULFATE  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  SEA-CUCUMBER  FUCOSE BRANCHES  BODY-WALL  INDEPENDENT INHIBITION  POLYSACCHARIDE ACCOUNT  FACTOR XASE  HEPARIN  
A regular fucan sulfate from Stichopus herrmanni and its peroxide depolymerization: Structure and anticoagulant activity 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 256, 页码: 117513
作者:  Li,Xiaomei;  Li,Shanni;  Liu,Jie;  Lin,Lisha;  Sun,Huifang;  Yang,Wenjiao;  Cai,Ying;  Gao,Na;  Zhou,Lutan;  Qin,Hongbo;  Yin,Ronghua;  Zhao,Jinhua
浏览  |  Adobe PDF(3183Kb)  |  收藏  |  浏览/下载：120/21  |  提交时间：2022/04/02
fucan sulfate  peroxide depolymerization  oligosaccharides  anti-thrombin activity  FUCOSYLATED CHONDROITIN SULFATE  FREE-RADICAL DEPOLYMERIZATION  PHYSICOCHEMICAL CHARACTERISTICS  REPEATING UNIT  BODY-WALL  SEA  FUCOIDAN  GLYCOSAMINOGLYCAN  POLYSACCHARIDES  HEPARIN  
NMR characterization and anticoagulant activity of the oligosaccharides from the fucosylated glycosaminoglycan isolated from Holothuria coluber 期刊论文
CARBOHYDRATE POLYMERS, 2020
作者:  Yang, Wenjiao;  Chen, Dingyuan;  He, Zhicheng;  Zhou, Lutan;  Cai, Ying;  Mao, Hui;  Gao, Na;  Zuo, Zhili;  Yin, Ronghua;  Zhao, Jinhua
浏览  |  Adobe PDF(2127Kb)  |  收藏  |  浏览/下载：204/74  |  提交时间：2021/01/05
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
浏览  |  Adobe PDF(4714Kb)  |  收藏  |  浏览/下载：370/47  |  提交时间：2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Physicochemical Characteristics and Anticoagulant Activities of the Polysaccharides from Sea Cucumber Pattalus mollis 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 15
作者:  Zheng, Wenqi;  Zhou, Lutan;  Lin, Lisha;  Cai, Ying;  Sun, Huifang;  Zhao, Longyan;  Gao, Na;  Yin, Ronghua;  Zhao, Jinhua
浏览  |  Adobe PDF(2958Kb)  |  收藏  |  浏览/下载：242/39  |  提交时间：2019/06/24
Pattalus mollis  fucosylated glycosaminoglycan  fucan sulfate  physicochemical characteristics  anticoagulant activities  
Structural Elucidation and Biological Activity of a Highly Regular Fucosylated Glycosaminoglycan from the Edible Sea Cucumber Stichopus herrmanni 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017, 卷号: 65, 期号: 42, 页码: 9315-9323
作者:  Li, Xiaomei;  Luo, Lan;  Cai, Ying;  Yang, Wenjiao;  Lin, Lisha;  Li, Zi;  Gao, Na;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(1246Kb)  |  收藏  |  浏览/下载：368/143  |  提交时间：2017/12/18
Sea Cucumber  Fucosylated Glycosaminoglycan  Chemical Structure  Anticoagulant  Stiehopus Herrmanni