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B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells 期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 18, 页码: 3371-3386
作者:  Zhou, Hongyu;  Yu, Chunlei;  Kong, Lingmei;  Xu, Xiaoliang;  Yan, Juming;  Li, Yingchao;  An, Tao;  Gong, Liang;  Gong, Yaxiao;  Zhu, Huifang;  Zhang, Hongbin;  Yang, Xiaodong;  Li, Yan
浏览  |  Adobe PDF(5225Kb)  |  收藏  |  浏览/下载：278/37  |  提交时间：2019/06/24
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:  Deng, Guogang;  Zhou, Bei;  Wang, Jing;  Chen, Zhuo;  Gong, Liang;  Gong, Yaxiao;  Wu, Dongmei;  Li, Yan;  Zhang, Hongbin;  Yang, Xiaodong
浏览  |  Adobe PDF(1727Kb)  |  收藏  |  浏览/下载：316/45  |  提交时间：2019/07/29
Diosgenin  Cholesterol  Dehydroepiandrosterone  Imidazolium salt  Antitumor activities  Structure-activity relationships  
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
作者:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
浏览  |  Adobe PDF(3138Kb)  |  收藏  |  浏览/下载：823/155  |  提交时间：2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
Synthesis and cytotoxic activity of novel tetrahydrobenzodifuran-imidazolium salt derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 8, 页码: 1808-1814
作者:  Zhang, Chao-Bo;  Liu, Yang;  Liu, Zheng-Fen;  Duan, Sheng-Zu;  Li, Min-Yan;  Chen, Wen;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(1192Kb)  |  收藏  |  浏览/下载：653/112  |  提交时间：2017/06/30
Tetrahydrobenzodifurans  Imidazolium Salts  Cytotoxic Activity  Cell Cycle  Apoptosis  
New cytotoxic and anti-inflammatory compounds isolated from Morus alba L. 期刊论文
NATURAL PRODUCT RESEARCH, 2015, 卷号: 29, 期号: 18, 页码: 1711-1718
作者:  Qin,Jing;  Fan,Min;  He,Juan;  Wu,Xing-De;  Peng,Li-Yan;  Su,Jia;  Cheng,Xiao;  Li,Yan;  Kong,Ling-Mei;  Li,Rong-Tao;  Zhao,Qin-Shi
浏览  |  Adobe PDF(626Kb)  |  收藏  |  浏览/下载：290/82  |  提交时间：2016/01/19
Morus Alba l  Soroceal b  Sanggenol q  Cytotoxic Activity  Anti-inflammatory Activity  
Synthesis and antitumor activity of novel N-substituted carbazole imidazolium salt derivatives 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Liu, Lan-Xiang;  Wang, Xue-Quan;  Zhou, Bei;  Yang, Li-Juan;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(1438Kb)  |  收藏  |  浏览/下载：1732/828  |  提交时间：2016/01/19
Hyperattenins A-I, bioactive polyprenylated acylphloroglucinols from Hypericum attenuatum Choisy 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 7, 页码: 5277-5287
作者:  Li,Dongyan;  Xue,Yongbo;  Zhu,Hucheng;  Li,Yan;  Sun,Bin;  Liu,Junjun;  Yao,Guangmin;  Zhang,Jinwen;  Du,Guang;  Zhang,Yonghui;  Zhang,YH (reprint author),Huazhong Univ Sci & Technol,Sch Pharm,Tongji Med Coll,Hubei Key Lab Nat Med Chem & Resource Evaluat,Wuhan 430030,Peoples R China.
浏览  |  Adobe PDF(1001Kb)  |  收藏  |  浏览/下载：372/184  |  提交时间：2015/06/29
Synthesis and antitumor activity of novel 2-substituted indoline imidazolium salt derivatives 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, 卷号: 13, 期号: 5, 页码: 1550-1557
作者:  Xu,Xiao-Liang;  Yu,Chun-Lei;  Chen,Wen;  Li,Ying-Chao;  Yang,Li-Juan;  Li,Yan;  Zhang,Hong-Bin;  Yang,Xiao-Dong;  Li,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.;  liyanb@mail.kib.ac.cn;  zhanghbyd@gmail.com;  xdyang@ynu.edu.cn
浏览  |  Adobe PDF(2117Kb)  |  收藏  |  浏览/下载：280/60  |  提交时间：2015/06/29
Novel 3-substituted fluorine imidazolium/triazolium salt derivatives: synthesis and antitumor activity 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 78, 页码: 63936-63944
作者:  Liu, Jin-Mei;  Wang, Min;  Zhou, Yun-Jing;  Yan, Ju-Ming;  Yang, Li-Juan;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(1168Kb)  |  收藏  |  浏览/下载：151/37  |  提交时间：2016/01/19
Synthesis and cytotoxic activity of novel 1-((indol-3-yl)methyl)-1H-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 21, 页码: 4926-4930
作者:  Xu, Xiao-Liang;  Wang, Jia;  Yu, Chun-Lei;  Chen, Wen;  Li, Ying-Chao;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong;  Li,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.;  liyanb@mail.kib.ac.cn;  zhanghbyd@gmail.com;  xdyang@ynu.edu.cn
浏览  |  Adobe PDF(670Kb)  |  收藏  |  浏览/下载：437/133  |  提交时间：2014/11/25
Indole  Imidazolium Salts  Structure-activity Relationships  Cell Apoptosis