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Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
Adobe PDF(11543Kb)  |  收藏  |  浏览/下载：29/11  |  提交时间：2024/07/17
Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction 期刊论文
NATURE CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 4, 页码: 468-+
作者:  Guo,Yingjie;  Zhang,Huan;  Yan,Chen;  Shen,Birong;  Zhang,Yue;  Guo,Xiangyang;  Sun,Sha;  Yu,Fan;  Yan,Jiayun;  Liu,Ronghe;  Zhang,Qianping;  Zhang,Di;  Liu,Haiyang;  Liu,Yang;  Zhang,Yaoyao;  Li,Wenlei;  Qin,Jiangyu;  Lv,He;  Wang,Zhaoxia;  Yuan,Yun;  Yang,Jie-Feng;  Zhong,Ya-Ting;  Gao,Song;  Zhou,Bing;  Liu,Lei;  Kong,Deling;  Hao,Xiaojiang;  Hu,Junjie;  Chen,Quan
浏览  |  Adobe PDF(25423Kb)  |  收藏  |  浏览/下载：35/17  |  提交时间：2024/07/25
ENDOPLASMIC-RETICULUM  PROVIDE INSIGHT  MITOFUSIN 2  MFN1  DYNAMICS  REQUIRES  DEFECTS  FISSION  CELLS  
Tabernaesine J, a Novel Vincamine-Type Indole Alkaloid with 6/5/6/6/6/5/5 Heptacyclic-Ring System Scaffold from Tabernaemontana pachysiphon 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2022, 卷号: 40, 期号: 4, 页码: 475-479
作者:  Yi,Wen-Fang;  Adelakun,Tiwalade A.;  Bai,Xue;  Zhang,Yu;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(1252Kb)  |  收藏  |  浏览/下载：183/64  |  提交时间：2022/04/02
Natural products  Alkaloids  Structure elucidation  Tabernaemontana pachysiphon  Tabernaesine J  BISINDOLE ALKALOIDS  A-I  ALGORITHM  
Hyperpatone A, a polycyclic polyprenylated acylphloroglucinol with a rare 8/6/5/6/5 pentacyclic skeleton from Hypericum patulum 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2022, 卷号: 21, 期号: 1, 页码: 140-146
作者:  Zhang, Feng;  Yang, Jue;  Yi, Ping;  Li, Ya-Nan;  Hao, Xiao-Jiang;  Yuan, Chun-Mao
浏览  |  Adobe PDF(754Kb)  |  收藏  |  浏览/下载：50/11  |  提交时间：2024/04/30
ASSISTED STRUCTURE ELUCIDATION  
Phylogenetic patterns suggest frequent multiple origins of secondary metabolites across the seed-plant 'tree of life' 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8, 期号: 4, 页码: nwaa105
作者:  Zhang,Yongzeng;  Deng,Tao;  Sun,Lu;  Landis,Jacob B.;  Moore,Michael J.;  Wang,Hengchang;  Wang,Yuehua;  Hao,Xiaojiang;  Chen,Jijun;  Li,Shenghong;  Xu,Maonian;  Puno,Pema-Tenzin;  Raven,Peter H.;  Sun,Hang
收藏  |  浏览/下载：139/0  |  提交时间：2022/04/02
secondary metabolites  phylogenetic tree  phylogenetic signal  co-diversification  evolution  bioprospecting  seed plants  DIVERSIFICATION  EVOLUTION  DIVERSITY  SIGNAL  ANGIOSPERMS  CHEMISTRY  DEFENSES  FOSSIL  KEYS  
Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 7, 页码: 1541-1545
作者:  Chen,Yan-Ni;  Ding,Xiao;  Li,Dong-Mei;  Sun,Mao;  Yang,Lei;  Zhang,Yu;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(1835Kb)  |  收藏  |  浏览/下载：106/24  |  提交时间：2022/04/02
Perforatactones D and E, two new C-20 quassinoids with potential activity to induce lysosomal biogenesis from the twigs of Harrisonia perforata (Blanco) Merr. 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 44, 页码: 9637-9640
作者:  Liu,Shuai;  Zhang,Cui-Shan;  Ran,Xiao-Qian;  Tang,Xiao-Han;  Guo,Ya-Rong;  Yan,Ying;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rong-Can;  Di,Ying-Tong
浏览  |  Adobe PDF(997Kb)  |  收藏  |  浏览/下载：145/47  |  提交时间：2022/04/02
PROMISING BIOLOGICAL-ACTIVITY  LIMONOIDS  CHROMONES  FRUITS  DRUG  
Hypermonones A-I, New Polyprenylated Acylphloroglucinols from Hypericum monogynum with Multidrug Resistance Reversal Activity 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 9, 页码: 2422-2432
作者:  Zeng,Yan-Rong;  Li,Ya-Nan;  Yang,Jue;  Yi,Ping;  Huang,Lei;  Huang,Lie-Jun;  Gu,Wei;  Hu,Zhan-Xing;  Li,Yan-Mei;  Yuan,Chun-Mao;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2840Kb)  |  收藏  |  浏览/下载：117/32  |  提交时间：2022/04/02
Hypericum monogynum  Phytochemistry  Structure elucidation  Biological activity  Multidrug resistance reversal activity  P-GLYCOPROTEIN  MODULATORS  CANCER  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2579Kb)  |  收藏  |  浏览/下载：193/64  |  提交时间：2023/09/08
Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 3, 页码: 357-364
作者:  Chen,Yan-Ni;  Ding,Xiao;  Li,Dong-Mei;  Lu,Qing-Yun;  Liu,Shuai;  Li,Ying-Yao;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(1584Kb)  |  收藏  |  浏览/下载：149/33  |  提交时间：2022/04/02