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Hepatic Stellate Celland Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis 期刊论文
ACS NANO, 2023, 卷号: 17, 期号: 23, 页码: 23608-23625
作者:  Niu,Xia;  Meng,Yanan;  Cui,Jinjin;  Li,Rui;  Ding,Xiao;  Niu,Bingyu;  Chang,Ge;  Xu,Ning;  Li,Guiling;  Wang,Yucheng;  Wang,Lulu
浏览  |  Adobe PDF(5563Kb)  |  收藏  |  浏览/下载：6/0  |  提交时间：2024/07/10
liver fibrosis  dihydrotanshinone I  hepaticstellate cells  vitamin A  cyclodextrin  liver microbiome  STRATEGY  THERAPY  TARGET  NANOPARTICLES  PATHWAY  
Atractylodinol prevents pulmonary fibrosis through inhibiting TGF-β receptor 1 recycling by stabilizing vimentin 期刊论文
MOLECULAR THERAPY, 2023, 卷号: 31, 期号: 10, 页码: 3015-3033
作者:  Hao,Mengjiao;  Guan,Zhuoji;  Zhang,Zhikang;  Ai,Haopeng;  Peng,Xing;  Zhou,Huihao;  Xu,Jun;  Gu,Qiong
浏览  |  Adobe PDF(8787Kb)  |  收藏  |  浏览/下载：14/3  |  提交时间：2024/07/25
INTERMEDIATE-FILAMENT PROTEIN  MECHANISMS  PATHWAYS  ADHESION  IDENTIFICATION  SMAD  
Discovery of nontriterpenoids from the rot roots of Panax notoginseng with cytotoxicity and their molecular docking study and experimental validation 期刊论文
RSC ADVANCES, 2023, 卷号: 13, 期号: 16, 页码: 11037-11043
作者:  Shang,Jia-Huan;  Qiao,Yi-Jun;  Zhu,Hong-Tao;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
浏览  |  Adobe PDF(521Kb)  |  收藏  |  浏览/下载：46/15  |  提交时间：2024/05/09
THERAPY  
RUNX1-Regulated Signaling Pathways in Ovarian Cancer 期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
作者:  Chen,Yuanzhi;  He,Yingying;  Liu,Shubai
浏览  |  Adobe PDF(1447Kb)  |  收藏  |  浏览/下载：34/12  |  提交时间：2024/05/09
Runt-related transcription factor 1 (RUNX1)  ovarian cancer  apoptosis  signaling pathways  clinical therapeutic target  GROWTH-FACTOR  TRANSCRIPTION FACTORS  STEM-CELLS  RUNX1  STAT3  FAMILY  ACTIVATION  APOPTOSIS  LEUKEMIA  SURVIVAL  
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 886
作者:  Chen,Yuanzhi;  He,Zhicheng;  Yang,Shuting;  Chen,Cheng;  Xiong,Wenyong;  He,Yingying;  Liu,Shubai
浏览  |  Adobe PDF(4466Kb)  |  收藏  |  浏览/下载：36/7  |  提交时间：2024/05/09
Runt-related transcription factor 1 (RUNX1)  High-grade serous ovarian carcinoma (HGSOC)  Apoptosis  EMT  Clinical therapeutic target  EPITHELIAL-MESENCHYMAL TRANSITIONS  HEPATOCELLULAR-CARCINOMA  TRANSCRIPTION FACTOR  TP53 MUTATIONS  UP-REGULATION  TUMOR-GROWTH  MIGRATION  PROLIFERATION  INVASION  FOXO1  
Diverse structures and antihepatoma effect of sesquiterpenoid dimers from Artemisia eriopoda by AKT/STAT signaling pathway 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 64
作者:  He,Xiaofeng;  Ma,Wenjing;  Hu,Jing;  Li,Tianze;  Geng,Changan;  Ma,Yunbao;  Wang,Mengfei;  Yang,Kexin;  Zhang,Xuemei;  Chen,Ji-Jun
浏览  |  Adobe PDF(1548Kb)  |  收藏  |  浏览/下载：44/10  |  提交时间：2024/05/09
Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1219362
作者:  Guo,Xiuping;  Li,Rui;  Cui,Jinjin;  Hu,Chujuan;  Yu,Haoyang;  Ren,Ling;  Cheng,Yangyang;  Jiang,Jiandong;  Ding,Xiao;  Wang,Lulu
浏览  |  Adobe PDF(7660Kb)  |  收藏  |  浏览/下载：45/11  |  提交时间：2024/05/09
Erigeron Breviscapus Injection  Dengzhanxixin  Erigeron Breviscapus (Vant  ) Hand  -mazz  Colorectal Cancer  Necroptosis  Drug Resistance  Tumor-necrosis-factor  Colorectal-cancer  Natural Compounds  Scutellarin  Apoptosis  Proliferation  Macrophages  Migration  Invasion  Therapy  
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
作者:  Ran,Xiaoqian;  Lu,Qing-Yun;  Li,Ying-Yao;  Pu,Xue-Xue;  Guo,Yarong;  Yuan,Ming-Rui;  Guan,Shi-Peng;  Sun,Mao;  Jiao,Lijin;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang;  Luo,Rongcan
浏览  |  Adobe PDF(10283Kb)  |  收藏  |  浏览/下载：10/5  |  提交时间：2024/07/30
Euphorbia peplus L  Euphorbiaceae  Ent-abietane diterpenoid  Euphejolkinolide A  Autophagy-lysosomal pathway  ALZHEIMERS-DISEASE  TAU PATHOLOGY  NEURODEGENERATION  DITERPENOIDS  INHIBITION  MECHANISMS  APOPTOSIS  CELASTROL  PROTEIN  SYSTEM  
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
浏览  |  Adobe PDF(7197Kb)  |  收藏  |  浏览/下载：8/3  |  提交时间：2024/07/30
PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE