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Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：145/47  |  提交时间：2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
Synthesis and anti-fibrotic effects of santamarin derivatives as cytotoxic agents against hepatic stellate cell line LX2 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 127994
作者:  Wang,Jin-Ping;  Li,Tian-Ze;  Huang,Xiao-Yan;  Geng,Chang-An;  Shen,Cheng;  Sun,Jin-Jin;  Xue,Dong;  Chen,Ji-Jun
浏览  |  Adobe PDF(567Kb)  |  收藏  |  浏览/下载：113/39  |  提交时间：2022/04/02
Santamarin derivatives  Anti-fibrotic effects  HSC-LX2  Extracellular matrix  NF-KAPPA-B  SESQUITERPENE LACTONES  LIVER FIBROSIS  STRUCTURE REQUIREMENT  BAY LEAF  ACTIVATION  
Abietane Diterpenoids with Antioxidative Damage Activity from Rosmarinus officinalis 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
作者:  Chen, Xing-Long;  Luo, Qing-Yi;  Hu, Wei-Yan;  Chen, Ji-Jun;  Zhang, Rong-Ping
浏览  |  Adobe PDF(1537Kb)  |  收藏  |  浏览/下载：151/35  |  提交时间：2021/01/05
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
作者:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1837Kb)  |  收藏  |  浏览/下载：230/42  |  提交时间：2019/09/10
Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 228-235
作者:  Yang, Tong-Hua;  Yan, De-Xiu;  Huang, Xiao-Yan;  Hou, Bo;  Ma, Yun-Bao;  Peng, Hua;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(2111Kb)  |  收藏  |  浏览/下载：316/53  |  提交时间：2019/09/10
Terminthia paniculata (Wall. ex G. Don) CY Wu & TL Ming  Anacardiaceae  Termipaniculatones A-F  Chalcone-flavonone heterodimers  Xanthine oxidase inhibitors  Anti-gout potency  
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
作者:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(3731Kb)  |  收藏  |  浏览/下载：238/52  |  提交时间：2019/06/24
Uncaria rhynchophylla  Catechin  Melatonin receptors  Metabolites  Antidepressant activity  
Bioinformatics analysis of differentially expressed genes in hepatocellular carcinoma cells exposed to Swertiamarin 期刊论文
JOURNAL OF CANCER, 2019, 卷号: 10, 期号: 26, 页码: 6526-6534
作者:  Tang, Haoran;  Ke, Yang;  Ren, Zongfang;  Lei, Xuefen;  Xiao, Shufeng;  Bao, Tianhao;  Shi, Zhitian;  Zou, Renchao;  Wu, Tiangen;  Zhou, Jian;  Geng, Chang-An;  Wang, Lin;  Chen, Jijun
浏览  |  Adobe PDF(2228Kb)  |  收藏  |  浏览/下载：169/43  |  提交时间：2020/03/24
swertiamarin  microarray  HepG2 cells  hepatocellular cancer  Jun  Stat3  
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 期号: 0, 页码: 381-393
作者:  Yang, Tong-Hua;  Ma, Yun-Bao;  Geng, Chang-An;  Yan, De-Xiu;  Huang, Xiao-Yan;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2088Kb)  |  收藏  |  浏览/下载：259/79  |  提交时间：2018/10/04
Depression  Magnolol Derivatives  Mt1/2 Receptors  Metabolites  Monoamine Neurotransmitter  
Bioassay-guided isolation of saikosaponins with agonistic activity on 5-hydroxytryptamine 2C receptor from Bupleurum chinense and their potential use for the treatment of obesity 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 6, 页码: 467-473
作者:  Sun Chang-Li;  Geng Chang-An;  Huang Xiao-Yan;  Ma Yun-Bao;  Zheng Xiao-Hong;  Yang Tong-Hua;  Chen Xing-Long;  Yin Xiu-Juan;  Zhang Xue-Mei;  Chen Ji-Jun
浏览  |  Adobe PDF(746Kb)  |  收藏  |  浏览/下载：292/103  |  提交时间：2017/10/23
Bupleurum Chinense  5-hydroxytryptamine 2c (5-ht2c) Receptor  Anti-obesity  Saikosaponins  
Chemical and biological comparison of different sections of Uncaria rhynchophylla (Gou-Teng) 期刊论文
EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2017, 卷号: 23, 期号: 1, 页码: 11-21
作者:  Zhang, Jian-Gang;  Geng, Chang-An;  Huang, Xiao-Yan;  Chen, Xing-Long;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(521Kb)  |  收藏  |  浏览/下载：393/78  |  提交时间：2017/06/30
Uncaria Rhynchophylla  Gou Teng  Lc-ms Analysis  Chemical Profiles  Mt1/2 And 5-ht1a/2c Receptors  Indole Alkaloids