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A Mushroom P450-Monooxygenase Enables Regioand Stereoselective Biocatalytic Synthesis of Epoxycyclohexenones 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 49
作者:  Yang,Yan-Long;  Zhou,Man;  Yang,Lin;  Gressler,Markus;  Rassbach,Johannes;  Wurlitzer,Jacob M.;  Zeng,Ying;  Gao,Kun;  Hoffmeister,Dirk
浏览  |  Adobe PDF(1998Kb)  |  收藏  |  浏览/下载：26/8  |  提交时间：2024/07/10
Biocatalysis  Biosynthesis  Cytochrome P450  Epoxycyclohexenone  Natural Products  OPPOSITE FACIAL SPECIFICITY  NATURAL-PRODUCTS  STREPTOMYCES LL-C10037  BIOSYNTHESIS  EPOXYQUINONE  CYTOCHROME-P450  FERMENTATION  PANEPOXYDONE  EPOXIDATION  INHIBITION  
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载：28/6  |  提交时间：2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPARα agonists by in silico studies and biochemical evaluation 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 2256867
作者:  Li,Yue;  Lv,Mengjia;  Shen,Meiling;  Gu,Xi;  Zhang,Li;  Liu,Xingyong;  Chen,Jing;  Gong,Likun;  Zuo,Zhili
浏览  |  Adobe PDF(3338Kb)  |  收藏  |  浏览/下载：14/1  |  提交时间：2024/07/31
NAFLD  PPAR alpha agonist  virtual screening  biochemical evaluation  FATTY-ACID OXIDATION  GROMACS  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：206/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Fluevirines E and F, two new alkaloids fromFlueggea virosa 期刊论文
NATURAL PRODUCT RESEARCH, 2020
作者:  Yang, Xi;  Liu, Jianwen;  Huo, Zongqing;  Yuwen, Huansha;  Li, Yan;  Zhang, Yu
浏览  |  Adobe PDF(806Kb)  |  收藏  |  浏览/下载：166/43  |  提交时间：2021/01/05
Blue genome: chromosome-scale genome reveals the evolutionary and molecular basis of indigo biosynthesis in Strobilanthes cusia 期刊论文
PLANT JOURNAL, 2020
作者:  Xu, Wei;  Zhang, Libin;  Cunningham, Anthony B.;  Li, Shan;  Zhuang, Huifu;  Wang, Yuhua;  Liu, Aizhong
浏览  |  Adobe PDF(3027Kb)  |  收藏  |  浏览/下载：164/47  |  提交时间：2021/01/05
Phenolic Amides with Immunomodulatory Activity from the Nonpolysaccharide Fraction of Lycium barbarum Fruits 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
作者:  Zhu, Pei-Feng;  Zhao, Yun-Li;  Dai, Zhi;  Qin, Xu-Jie;  Yuan, Hai-Lian;  Jin, Qiong;  Wang, Yi-Fen;  Liu, Ya-Ping;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1621Kb)  |  收藏  |  浏览/下载：247/98  |  提交时间：2021/01/05
Synthesis and antitumor activity of camptothecin-4 beta-triazolopodophyllotoxin conjugates 期刊论文
NATURAL PRODUCT RESEARCH, 2020
作者:  Zi, Cheng-Ting;  Yang, Liu;  Dong, Fa-Wu;  Kong, Qing-Hua;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Hu, Jiang-Miao
浏览  |  Adobe PDF(1138Kb)  |  收藏  |  浏览/下载：278/71  |  提交时间：2021/01/05
Tagitinin A from Tithonia diversifolia provides resistance to tomato spotted wilt orthotospovirus by inducing systemic resistance 期刊论文
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2020
作者:  Zhao, Lihua;  Hu, Zhonghui;  Li, Shunlin;  Zhang, Lizhen;  Yu, Ping;  Zhang, Jie;  Zheng, Xue;  Rahman, Siddiqur;  Zhang, Zhongkai
浏览  |  Adobe PDF(1723Kb)  |  收藏  |  浏览/下载：231/90  |  提交时间：2021/01/05
Genomic insights into adaptation to heterogeneous environments for the ancient relictualCircaeaster agrestis(Circaeasteraceae, Ranunculales) 期刊论文
NEW PHYTOLOGIST, 2020
作者:  Zhang, Xu;  Sun, Yanxia;  Landis, Jacob B.;  Zhang, Jianwen;  Yang, Linsen;  Lin, Nan;  Zhang, Huajie;  Guo, Rui;  Li, Lijuan;  Zhang, Yonghong;  Deng, Tao;  Sun, Hang;  Wang, Hengchang
浏览  |  Adobe PDF(2221Kb)  |  收藏  |  浏览/下载：230/82  |  提交时间：2021/01/05