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Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 卷号: 21, 期号: 10, 页码: 977-984
作者:  Li, Xing-Ren;  Fu, Qiang;  Zhou, Min;  Hu, Kun;  Du, Xue;  Li, Xiao-Nian;  Sun, Han-Dong;  Yue, Jian-Bo;  Zhang, Hong-Bin;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1263Kb)  |  收藏  |  浏览/下载：278/60  |  提交时间：2019/10/28
Lamiaceae  ent-clerodane diterpenoids  Isodon scoparius  X-ray diffraction  autophagic activity  
Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.;  Wang, Wei-Guang;  Sun, Han-Dong;  Lillico, Ryan;  Lakowski, Ted M.;  Siahaan, Teruna J.;  Davies, Neal M.;  Puno, Pema-Tenzin;  Vanan, Magimairajan Issai;  Miller, Donald W.
浏览  |  Adobe PDF(3895Kb)  |  收藏  |  浏览/下载：249/63  |  提交时间：2019/12/20
blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma  
(+)- and (-)-Alternarilactone A: Enantiomers with a Diepoxy-Cage-like Scaffold from an Endophytic Alternaria sp. 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 4, 页码: 735-740
作者:  Tang, Jian-Wei;  Xu, Hou-Chao;  Wang, Wei-Guang;  Hu, Kun;  Zhou, Yuan-Fei;  Chen, Rong;  Li, Xiao-Nian;  Du, Xue;  Sun, Han-Dong;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1213Kb)  |  收藏  |  浏览/下载：354/42  |  提交时间：2019/06/24
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：346/77  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Phytochemistry and pharmacology of the genus Leonurus: The herb to benefit the mothers and more 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 147, 页码: 167-183
作者:  Zhang, Rui-Han;  Liu, Zhi-Ke;  Yang, Da-Song;  Zhang, Xing-Jie;  Sun, Han-Dong;  Xiao, Wei-Lie
收藏  |  浏览/下载：355/0  |  提交时间：2018/05/08
Leonurus  Lamiaceae  Leonurine  Labdane Diterpenoids  Traditional Chinese Medicine  Anti-gynecological Disorder  Cardiovascular Protection  Anti-inflammation  
Rabdocoestin B exhibits antitumor activity by inducing G2/M phase arrest and apoptosis in esophageal squamous cell carcinoma 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018, 卷号: 81, 期号: 3, 页码: 469-481
作者:  Wang, Jingnan;  Zhang, Zhirong;  Che, Yun;  Yuan, Zuyang;  Lu, Zhiliang;  Li, Yuan;  Wan, Jun;  Sun, Handong;  Chen, Zhaoli;  Pu, Jianxin;  He, Jie
收藏  |  浏览/下载：309/0  |  提交时间：2018/05/08
Rabdocoestin b  G2/m Phase Arrest  Apoptosis  Cytotoxicity  Esophageal Squamous Cell Carcinoma  
Structurally Diverse Diterpenoids from lsodon scoparius and Their Bioactivity 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 7, 页码: 2026-2036
作者:  Jiang, Hua-Yi;  Wang, Wei-Guang;  Tang, Jian-Wei;  Liu, Miao;  Li, Xing-Ren;  Hu, Kun;  Du, Xue;  Li, Xiao-Nian;  Zhang, Hong-Bin;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(1786Kb)  |  收藏  |  浏览/下载：460/78  |  提交时间：2017/10/23
Ent-kaurane Diterpenoids  Isodon-scoparius  Cytotoxic Diterpenoids  Abietane Diterpenoids  Eriocalyxin-b  Derivatives  Laxiflora  Growth  
Efficient Semisynthesis of (-)-Pseudoirroratin A from (-)-Flexicaulin A and Assessment of Their Antitumor Activities 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 3, 页码: 372-376
作者:  Guo, Lei;  Tsang, Siu Wai;  Zhang, Tong-Xin;  Liu, Kang-Lun;  Guan, Yi-Fu;  Wang, Bo;  Sun, Han-Dong;  Zhang, Hong-Jie;  Wong, Man Shing
浏览  |  Adobe PDF(1840Kb)  |  收藏  |  浏览/下载：262/61  |  提交时间：2017/05/19
(-)-pseudoirroratin a  (-)-flexicaulin a  Apoptosis  Antitumor Activity  
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
浏览  |  Adobe PDF(13632Kb)  |  收藏  |  浏览/下载：366/40  |  提交时间：2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
瘿花甲素对S180细胞抗肿瘤活性及其细胞周期的影响 期刊论文
中南药学, 2016, 期号: 11, 页码: 1202-1205
作者:  杨焕芝;  周轶平;  翁稚颖;  罗敏;  孙汉董;  李玛琳
浏览  |  Adobe PDF(2312Kb)  |  收藏  |  浏览/下载：495/109  |  提交时间：2016/12/19
瘿花甲素  S180细胞  小鼠移植性肿瘤  细胞周期  抗肿瘤活性