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The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
作者:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
收藏  |  浏览/下载：78/0  |  提交时间：2022/04/02
Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2120Kb)  |  收藏  |  浏览/下载：222/51  |  提交时间：2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
作者:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
浏览  |  Adobe PDF(5546Kb)  |  收藏  |  浏览/下载：135/46  |  提交时间：2022/04/02
Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Pharmacological effects of indole alkaloids from Alstonia scholaris (L.) R. Br. on pulmonary fibrosis in vivo 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 267, 页码: 113506
作者:  Zhao,Yun-Li;  Pu,Shi-Biao;  Qi,Yan;  Wu,Bai-Fen;  Shang,Jian-Hua;  Liu,Ya-Ping;  Hu,Di;  Luo,Xiao-Dong
浏览  |  Adobe PDF(9993Kb)  |  收藏  |  浏览/下载：107/34  |  提交时间：2022/04/02
Alstonia scholaris  Indole alkaloids  Pulmonary fibrosis  Picrinine  Vallesamine  Scholaricine  19-Epischolaricine  FLIGHT MASS-SPECTROMETRY  ACUTE LUNG INJURY  AIRWAY INFLAMMATION  OXIDATIVE STRESS  BARK EXTRACTS  LEAVES  CONSTITUENTS  COLLAGEN  LEAF  KL-6  
Phenolic Amides with Immunomodulatory Activity from the Nonpolysaccharide Fraction of Lycium barbarum Fruits 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
作者:  Zhu, Pei-Feng;  Zhao, Yun-Li;  Dai, Zhi;  Qin, Xu-Jie;  Yuan, Hai-Lian;  Jin, Qiong;  Wang, Yi-Fen;  Liu, Ya-Ping;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1621Kb)  |  收藏  |  浏览/下载：228/90  |  提交时间：2021/01/05
Anti-inflammatory and antinociceptive effects of Curcuma kwangsiensis and its bioactive terpenoids in vivo and in vitro 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020
作者:  Yuan, Hai-Lian;  Zhao, Yun-Li;  Ding, Cai-Feng;  Zhu, Pei-Feng;  Jin, Qiong;  Liu, Ya-Ping;  Ding, Zhong-Tao;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1279Kb)  |  收藏  |  浏览/下载：175/102  |  提交时间：2021/01/05
Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020
作者:  Zhao, Yun-Li;  Yang, Zi-Feng;  Wu, Bai-Fen;  Shang, Jian-Hua;  Liu, Ya-Ping;  Wang, Xin-Hua;  Luo, Xiao-Dong
浏览  |  Adobe PDF(4071Kb)  |  收藏  |  浏览/下载：194/71  |  提交时间：2021/01/05
Total alkaloids from Alstonia scholaris inhibit influenza a virus replication and lung immunopathology by regulating the innate immune response 期刊论文
PHYTOMEDICINE, 2020
作者:  Zhou, Hong-Xia;  Li, Run-Feng;  Wang, Yi-Feng;  Shen, Li-Han;  Cai, Li-Hua;  Weng, Yun-Ceng;  Zhang, Huan-Rong;  Chen, Xin-Xin;  Wu, Xiao;  Chen, Rui-Feng;  Jiang, Hai-Ming;  Wang, Caiyun;  Yang, Mingrong;  Lu, Jingguang;  Luo, Xiao-Dong;  Jiang, Zhihong;  Yang, Zi-Feng
浏览  |  Adobe PDF(841Kb)  |  收藏  |  浏览/下载：171/41  |  提交时间：2021/01/05
Comparative investigation of phytochemicals among ten citrus herbs by ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry and evaluation of their antioxidant properties 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2020
作者:  He, Ying-Jie;  Zhu, Meng;  Zhou, Ying;  Zhao, Kang-Hong;  Zhou, Jia-Li;  Qi, Zi-Heng;  Zhu, Yan-Yan;  Wang, Zhao-Jie;  Xie, Tian-Zhen;  Tang, Qi;  Wang, Yi-Fen;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1202Kb)  |  收藏  |  浏览/下载：181/78  |  提交时间：2021/01/05
Anti-inflammatory and analgesic activities of Neolamarckia cadamba and its bioactive monoterpenoid indole alkaloids 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020
作者:  Yuan, Hai-Lian;  Zhao, Yun-Li;  Qin, Xu-Jie;  Liu, Ya-Ping;  Yu, Hao-Fei;  Zhu, Pei-Feng;  Jin, Qiong;  Yang, Xing-Wei;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1569Kb)  |  收藏  |  浏览/下载：166/71  |  提交时间：2021/01/05