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A Novel Histone Acetyltransferase Inhibitor Modulating Gcn5 Network:Cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone 期刊论文
J. Med. Chem, 2009, 卷号: 52, 期号: 0, 页码: 530–536
作者:  Franco Chimenti;  Bruna Bizzarri;  Elias Maccioni;  Daniela Secci;  Adriana Bolasco;  Paola Chimenti;  Rossella Fioravanti;  Arianna Granese;  Simone Carradori;  Federica Tosi;  Paola Ballario;  Stefano Vernarecci;  Patrizia Filetici
Adobe PDF(666Kb)  |  收藏  |  浏览/下载:73/2  |  提交时间:2017/07/24
Parallel Solution-Phase and Microwave-Assisted Synthesis of New S-DABODerivatives Endowed with Subnanomolar Anti-HIV-1 Activity 期刊论文
J. Med. Chem, 2005, 卷号: 48, 页码: 8000-8008
作者:  John A. Darling;  Michael J. Blum
Adobe PDF(216Kb)  |  收藏  |  浏览/下载:33/0  |  提交时间:2017/07/19
6-[1-(2,6-Difluorophenyl)ethyl]pyrimidinonesAntagonize Cell Proliferationand Induce Cell Differentiation byInhibiting (a Nontelomeric) EndogenousReverse Transcriptase 期刊论文
J. Med. Chem., 2005, 卷号: 48, 页码: 6776-6778
作者:  Julia Kruger;  Colwyn M. Thomas;  Catherine Golstein;  Mark S. Dixon;  Matthew Smoker;  Saijun Tang;  Lonneke Mulder;  Jonathan D. G. Jones
Adobe PDF(232Kb)  |  收藏  |  浏览/下载:45/0  |  提交时间:2017/07/19
Computer-Aided Design, Synthesis, and Anti-HIV-1 Activity in Vitro of2-Alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as Novel Potent Non-Nucleoside Reverse Transcriptase Inhibitors, AlsoActive Against the Y181C Variant 期刊论文
J. Med. Chem., 2004, 卷号: 47, 页码: 928-934
作者:  JULIA A. KLEIN;  JOHN HARTE;  XIN-QUAN ZHAO
Adobe PDF(218Kb)  |  收藏  |  浏览/下载:50/0  |  提交时间:2017/07/19
Flavonolignan and Flavone Inhibitors of a Staphylococcus aureusMultidrug Resistance Pump: Structure−Activity Relationships 期刊论文
J. Med. Chem., 2001, 卷号: 44, 页码: 261-268
作者:  Juan Pedro M. Camacho;  Timothy F. Sharbel;  Leo W. Beukeboom
Adobe PDF(223Kb)  |  收藏  |  浏览/下载:45/1  |  提交时间:2017/07/19
Synthesis and antineoplastic activity of cyclolignan aldehydes 期刊论文
Eur. J. Med. Chem, 2000, 卷号: 35, 页码: 691−698
作者:  Greta A.Fryxell;  Grethe R.Hasle
Adobe PDF(144Kb)  |  收藏  |  浏览/下载:64/2  |  提交时间:2017/07/19
5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4(3H)-ones:Novel Potent and Selective Dihydro-alkoxy-benzyl-oxopyrimidine Derivatives 期刊论文
J. Med. Chem., 1999, 卷号: 42, 页码: 619-627
作者:  Jose L. Perez;  Latika Khatri;  Craig Chang;  Sapna Srivastava;  Pavel Osten;  Edward B. Ziff
Adobe PDF(100Kb)  |  收藏  |  浏览/下载:80/0  |  提交时间:2017/07/19
Synthesis and Biological Evaluation of Dihydrobenzofuran Lignans and RelatedCompounds as Potential Antitumor Agents that Inhibit Tubulin Polymerization 期刊论文
J. Med. Chem, 1999, 卷号: 42, 页码: 5475-5481
作者:  John A. Ryals;  Urs H. Neuenschwander;  Michael G. Willits;  Antonio Molina;  Henry-York Steiner;  Michelle D. Hunt
Adobe PDF(129Kb)  |  收藏  |  浏览/下载:94/0  |  提交时间:2017/07/19
Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: Novel Non-NucleosideReverse Transcriptase Inhibitors of the S-DABO Series 期刊论文
J. Med. Chem., 1997, 卷号: 40, 页码: 1447-1454
作者:  John Warren Huntley;  Michał Kowalewski
Adobe PDF(264Kb)  |  收藏  |  浏览/下载:39/0  |  提交时间:2017/07/19
Betulinic Acid Derivatives: A New Class of Specific Inhibitors of HumanImmunodeficiency Virus Type 1 Entry 期刊论文
J. Med. Chem., 1996, 卷号: 39, 期号: 0, 页码: 1069-1083
作者:  Francüoise Soler;  Christele Poujade;  Michel Evers;  Jean-Christophe Carry;  Yvette Henin;  Anne Bousseau;  Thierry Huet;  Rudi Pauwels;  Erik De Clercq;  ean-Francüois Mayaux;  Jean-Bernard Le Pecq;  Norbert Dereu
Adobe PDF(450Kb)  |  收藏  |  浏览/下载:70/0  |  提交时间:2017/07/21