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The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein 期刊论文
CELL DEATH AND DIFFERENTIATION, 2020, 卷号: 27, 期号: 2, 页码: 632-645
作者:  Hua, Xiaohui;  Huang, Maowen;  Deng, Xu;  Xu, Jiheng;  Luo, Yisi;  Xie, Qipeng;  Xu, Jiawei;  Tian, Zhongxian;  Li, Jingxia;  Zhu, Junlan;  Huang, Chao;  Zhao, Qin-shi;  Huang, Haishan;  Huang, Chuanshu
收藏  |  浏览/下载：261/0  |  提交时间：2020/03/24
Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10
作者:  Li, Penghua;  He, Haiqing;  Zhang, Yunqin;  Yang, Rui;  Xu, Lili;  Chen, Zixi;  Huang, Yingying;  Bao, Limei;  Xiao, Guozhi
收藏  |  浏览/下载：136/0  |  提交时间：2020/03/24
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：206/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Aromatization of natural products by a specialized detoxification enzyme 期刊论文
NATURE CHEMICAL BIOLOGY, 2020, 卷号: 16, 期号: 3, 页码: 11
作者:  Huang, Jin-Quan;  Fang, Xin;  Tian, Xiu;  Chen, Ping;  Lin, Jia-Ling;  Guo, Xiao-Xiang;  Li, Jian-Xu;  Fan, Zhen;  Song, Wei-Meng;  Chen, Fang-Yan;  Ahati, Ruzha;  Wang, Ling-Jian;  Zhao, Qing;  Martin, Cathie;  Chen, Xiao-Ya
收藏  |  浏览/下载：185/0  |  提交时间：2020/03/18
Pu-Erh Tea Relaxes the Thoracic Aorta of Rats by Reducing Intracellular Calcium 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 13
作者:  Luo, Dan;  Chen, Xuejiao;  Zhu, Xu;  Liu, Shuang;  Li, Jie;  Xu, Jianping;  Zhao, Jinhua;  Ji, Xu
浏览  |  Adobe PDF(4082Kb)  |  收藏  |  浏览/下载：405/50  |  提交时间：2020/03/18
endothelium-independent vasodilation  hypertension  pu-erh tea  tea components  theabrownins  
Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 166, 页码: 11
作者:  Fan, Min;  Luo, Dan;  Peng, Li-Yan;  Li, Xiao-Nian;  Wu, Xing-De;  Ji, Xu;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1457Kb)  |  收藏  |  浏览/下载：259/72  |  提交时间：2019/10/28
Salvia hispanica L. (Lamiaceae)  Chia  Neo-clerodane diterpenoids  Hispanins A-J  Single crystal X-ray diffraction analysis  Cardioprotective effects  
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：262/51  |  提交时间：2020/03/26
Canescones A-E: aromatic polyketide dimers with PTP1B inhibitory activity from Penicillium canescens 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 18, 页码: 3274-3281
作者:  Zang, Yi;  Gong, Yi-Hua;  Li, Xu-Wen;  Li, Xiao-Nian;  Liu, Jun-Jun;  Chen, Chun-Mei;  Zhou, Yuan;  Gu, Liang-Hu;  Luo, Zeng-Wei;  Wang, Jian-Ping;  Sun, Wei-Guang;  Zhu, Hu-Cheng;  Zhang, Yong-Hui
浏览  |  Adobe PDF(2538Kb)  |  收藏  |  浏览/下载：232/55  |  提交时间：2019/10/28
New anti-HBV norbisabolane sesquiterpenes from Phyllantus acidus 期刊论文
FITOTERAPIA, 2019, 卷号: 137, 页码: 7
作者:  Gu, Chen;  Yin, Ai-Ping;  Yuan, Hao-Yang;  Yang, Kong;  Luo, Jia;  Zhan, Ying-Jun;  Yang, Chong-Ren;  Zuo, Da-Min;  Li, Hai-Zhou;  Xu, Min
浏览  |  Adobe PDF(822Kb)  |  收藏  |  浏览/下载：184/36  |  提交时间：2019/10/28
Phyllanthus acidus  Norbisabolane-type sesquiterpenoid  Anti-HBV  
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3136Kb)  |  收藏  |  浏览/下载：203/67  |  提交时间：2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity