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Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 19, 页码: 3428-3434
作者:  Ding, Cai-Feng;  Zhang, Rong-Ping;  Yu, Hao-Fei;  Yang, Jing;  Qin, Xu-Jie;  Dai, Zhi;  Liu, Ya-Ping;  Lu, Qiu-Min;  Lai, Ren;  Luo, Xiao-Dong
浏览  |  Adobe PDF(2565Kb)  |  收藏  |  浏览/下载：266/38  |  提交时间：2019/11/07
Erythrina alkaloids from leaves of Erythrina arborescens 期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 38, 页码: 6
作者:  Zhang, Bing-Jie;  Xiao, Wen-Na;  Chen, Jing;  Bao, Mei-Fen;  Schinnerl, Johann;  Wang, Qi;  Cai, Xiang-Hai
浏览  |  Adobe PDF(389Kb)  |  收藏  |  浏览/下载：267/51  |  提交时间：2019/12/20
Erythrina arborescens  Erythrivarines H-I  Alkaloid glucosides  Xanthine oxidase inhibitor  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：276/81  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
A new erythrinan N-oxide alkaloid from Erythrina stricta 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 14, 页码: 2004-2010
作者:  Wu, Jing;  Zhang, Bing-Jie;  Bao, Mei-Fen;  Cai, Xiang-Hai
浏览  |  Adobe PDF(1025Kb)  |  收藏  |  浏览/下载：270/142  |  提交时间：2019/03/25
Erythrina stricta  erythrinan alkaloids  11 beta-hydroxyerythratidine N-oxide  
Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities 期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 12, 页码: 1711-1716
作者:  Hu, Zhan-Xing;  Tang, Hong-Yu;  Guo, Jie;  Aisa, Haji Aker;  Zhang, Yu;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(766Kb)  |  收藏  |  浏览/下载：207/43  |  提交时间：2019/07/29
Stemona tuberosa  Stemona alkaloids  Stemtuberline A  Anti-TMV  
Nukiangendines A and B, two novel 13,14-seco-abietanes from Abies nukiangensis 期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 10, 页码: 751-753
作者:  Li, Yong-Li;  Zhang, Qiang;  Wu, Jian-Jun;  Xue, Li-Jun;  Chen, Li-Ming;  Tian, Jun-Mian;  Xu, Zhuo-Ni;  Chen, Ying;  Yang, Xian-Wen;  Hao, Xiao-Jiang;  Li, Jie
浏览  |  Adobe PDF(561Kb)  |  收藏  |  浏览/下载：289/42  |  提交时间：2019/04/15
Abies nukiangensis  seco-Abietane  Diterpene  Antiviral  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：365/54  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：345/77  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Premnafulvol A: A Diterpenoid with a 6/5/7/3-Fused Tetracyclic Core and Its Biosynthetically Related Analogues from Premna fulva 期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 19, 页码: 6314-6317
作者:  Pu, De-Bing;  Du, Bao-Wen;  Chen, Wen;  Gao, Jun-Bo;  Hu, Kun;  Shi, Nan;  Li, Yi-Ming;  Zhang, Xing-Jie;  Zhang, Rui-Han;  Li, Xiao-Nian;  Zhang, Hong-Bin;  Wang, Fei;  Xiao, Wei-Lie
收藏  |  浏览/下载：194/0  |  提交时间：2018/11/12
In Vitro Human Dihydroorotate Dehydrogenase Inhibitory, Anti-inflammatory and Cytotoxic Activities of Alkaloids from the Seeds of Nigella glandulifera 期刊论文
PLANTA MEDICA, 2018, 卷号: 84, 期号: 14, 页码: 1013-1021
作者:  Gao, Jun-Bo;  Zhang, Xing-Jie;  Zhang, Rui-Han;  Zhu, Li-Li;  Pu, De-Bing;  Li, Xiao-Li;  Li, Hong-Lin;  Xu, Min;  Xiao, Wei-Lie
收藏  |  浏览/下载：116/0  |  提交时间：2018/10/22
dolabellane-type diterpene alkaloids  Ranunculaceae  Nigella glandulifera  human dihydroorotate dehydrogenase  lipopolysaccharide  nitric oxide production  cytotoxic activity