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Three new dammarane-type triterpenoid saponins and their cytotoxicity from steamed Panax notoginseng | |
Yao, Yi -Fei; Ni, Wei; Zhou, Yong-Sheng; Yan, Huan; Liu, Hai -Yang | |
2024 | |
发表期刊 | PHYTOCHEMISTRY LETTERS
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ISSN | 1874-3900 |
卷号 | 62页码:1-5 |
摘要 | Three new dammarane-type triterpenoid saponins, namely 6 '-crotonyl-(20 S)-ginsenoside Rg3 (1), 6 '-crotonyl(20 R)-ginsenoside Rg3 (2), and notoginsenolide A (3), were isolated from the steamed Panax notoginseng. Among them, 3 is the first tetranordamarane triterpenoid glucoside with an alpha, beta-unsaturated gamma-lactone group. The three isolates were evaluated for their cytotoxicities against five human cancer cell lines (HL-60, A-549, SMMC-7721, MDA-MB-231, and SW480). The results showed that compound 1 had moderate cytotoxicity against HL-60 cell line with an IC50 value of 23.39 mu M. |
DOI | 10.1016/j.phytol.2024.06.001 |
WOS记录号 | WOS:001258267400001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/76390 |
专题 | 中国科学院昆明植物研究所 |
推荐引用方式 GB/T 7714 | Yao, Yi -Fei,Ni, Wei,Zhou, Yong-Sheng,et al. Three new dammarane-type triterpenoid saponins and their cytotoxicity from steamed Panax notoginseng[J]. PHYTOCHEMISTRY LETTERS,2024,62:1-5. |
APA | Yao, Yi -Fei,Ni, Wei,Zhou, Yong-Sheng,Yan, Huan,&Liu, Hai -Yang.(2024).Three new dammarane-type triterpenoid saponins and their cytotoxicity from steamed Panax notoginseng.PHYTOCHEMISTRY LETTERS,62,1-5. |
MLA | Yao, Yi -Fei,et al."Three new dammarane-type triterpenoid saponins and their cytotoxicity from steamed Panax notoginseng".PHYTOCHEMISTRY LETTERS 62(2024):1-5. |
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10.1016_j.phytol.202(862KB) | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 |
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