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Three new dammarane-type triterpenoid saponins and their cytotoxicity from steamed Panax notoginseng
Yao, Yi -Fei; Ni, Wei; Zhou, Yong-Sheng; Yan, Huan; Liu, Hai -Yang
2024
发表期刊PHYTOCHEMISTRY LETTERS
ISSN1874-3900
卷号62页码:1-5
摘要Three new dammarane-type triterpenoid saponins, namely 6 '-crotonyl-(20 S)-ginsenoside Rg3 (1), 6 '-crotonyl(20 R)-ginsenoside Rg3 (2), and notoginsenolide A (3), were isolated from the steamed Panax notoginseng. Among them, 3 is the first tetranordamarane triterpenoid glucoside with an alpha, beta-unsaturated gamma-lactone group. The three isolates were evaluated for their cytotoxicities against five human cancer cell lines (HL-60, A-549, SMMC-7721, MDA-MB-231, and SW480). The results showed that compound 1 had moderate cytotoxicity against HL-60 cell line with an IC50 value of 23.39 mu M.
DOI10.1016/j.phytol.2024.06.001
WOS记录号WOS:001258267400001
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/76390
专题中国科学院昆明植物研究所
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GB/T 7714
Yao, Yi -Fei,Ni, Wei,Zhou, Yong-Sheng,et al. Three new dammarane-type triterpenoid saponins and their cytotoxicity from steamed Panax notoginseng[J]. PHYTOCHEMISTRY LETTERS,2024,62:1-5.
APA Yao, Yi -Fei,Ni, Wei,Zhou, Yong-Sheng,Yan, Huan,&Liu, Hai -Yang.(2024).Three new dammarane-type triterpenoid saponins and their cytotoxicity from steamed Panax notoginseng.PHYTOCHEMISTRY LETTERS,62,1-5.
MLA Yao, Yi -Fei,et al."Three new dammarane-type triterpenoid saponins and their cytotoxicity from steamed Panax notoginseng".PHYTOCHEMISTRY LETTERS 62(2024):1-5.
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