Active Constituents with Tyrosinase Inhibitory Activities from Waste Tobacco Leaves

doi:10.1002/cbdv.202400463

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	Active Constituents with Tyrosinase Inhibitory Activities from Waste Tobacco Leaves
	Zhang, Mei; Sun, Jia-Yu; Qiu, Hong-Mao; Zhang, Peng; Deng, Lu-Lu; Li, Jiang; Hao, Xiao-Jiang; Su, Xian-Kun; Mu, Shu-Zhen
	2024
发表期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1872
卷号	21 期号:6 页码:-
摘要	One novel compound, (R)-3, 6-diethoxy-4-hydroxycyclohex-3-en-1-one (1) and thirteen known compounds were isolated from the waste tobacco leaves. The structures of two compounds (1-2) were confirmed and attributed firstly by the extensive spectroscopic data, including 1D/2D NMR, IR, HR-ESI-MS, CD, and ECD spectra. Notably, seven compounds (2, 3, 9, 10, 11, 12, and 13) exhibited better tyrosinase inhibitory activity than the positive control kojic acid. The binding modes of these compounds revealed that their structure formed strong hydrogen bonds and van der Waals forces with the active sites of tyrosinase. These results indicated that waste tobacco leaves are good resources for developing tyrosinase inhibitors.
DOI	10.1002/cbdv.202400463
WOS记录号	WOS:001215043500001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/76340
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Zhang, Mei,Sun, Jia-Yu,Qiu, Hong-Mao,et al. Active Constituents with Tyrosinase Inhibitory Activities from Waste Tobacco Leaves[J]. CHEMISTRY & BIODIVERSITY,2024,21(6):-.
APA	Zhang, Mei.,Sun, Jia-Yu.,Qiu, Hong-Mao.,Zhang, Peng.,Deng, Lu-Lu.,...&Mu, Shu-Zhen.(2024).Active Constituents with Tyrosinase Inhibitory Activities from Waste Tobacco Leaves.CHEMISTRY & BIODIVERSITY,21(6),-.
MLA	Zhang, Mei,et al."Active Constituents with Tyrosinase Inhibitory Activities from Waste Tobacco Leaves".CHEMISTRY & BIODIVERSITY 21.6(2024):-.

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