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Artemdubosides A-G, seven unusual polyacetylenes from Artemisia dubia var. subdigitata and their antihepatoma activity
Yang, Ke-Xin; Ma, Yun-Bao; Li, Tian-Ze; Wang, Meng -Fei; Li, Feng-Jiao; Chen, Ji-Jun
2024
发表期刊FITOTERAPIA
ISSN0367-326X
卷号175页码:105909
摘要Artemdubosides A-E (1-5), the first examples of natural polyacetylenes substituted by 6'-O-crotonyl ss-glucopyranoside, and artemdubosides F-G (6-7) that were two unusual polyacetylenes featuring a 6'-O-acetyl ss-glucopyranoside moiety, were isolated from Artemisia dubia var. subdigitata. Their structures were elucidated based on the spectral data including HRESIMS, UV, IR, 1D and 2D NMR, and ECD calculations. Antihepatoma assay suggested that compound 1 exhibited activity against HepG2, Huh7, and SK-Hep-1 cells with inhibitory ratios of 77.1%, 90.8%, and 73.1% at 200.0 mu M, respectively.
DOI10.1016/j.fitote.2024.105909
WOS记录号WOS:001221866500001
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/76305
专题中国科学院昆明植物研究所
推荐引用方式
GB/T 7714
Yang, Ke-Xin,Ma, Yun-Bao,Li, Tian-Ze,et al. Artemdubosides A-G, seven unusual polyacetylenes from Artemisia dubia var. subdigitata and their antihepatoma activity[J]. FITOTERAPIA,2024,175:105909.
APA Yang, Ke-Xin,Ma, Yun-Bao,Li, Tian-Ze,Wang, Meng -Fei,Li, Feng-Jiao,&Chen, Ji-Jun.(2024).Artemdubosides A-G, seven unusual polyacetylenes from Artemisia dubia var. subdigitata and their antihepatoma activity.FITOTERAPIA,175,105909.
MLA Yang, Ke-Xin,et al."Artemdubosides A-G, seven unusual polyacetylenes from Artemisia dubia var. subdigitata and their antihepatoma activity".FITOTERAPIA 175(2024):105909.
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