Novel umami peptides from two Termitomyces mushrooms and molecular docking to the taste receptor T1R1/T1R3

doi:10.26599/FSHW.2022.9250091

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	Novel umami peptides from two Termitomyces mushrooms and molecular docking to the taste receptor T1R1/T1R3
	Zhang, Lanyun; Zhang, Li; Perez-Moreno, Jesus; Bin, Lu; Zhang, Fengming; Yu, Fuqiang
	2024
发表期刊	FOOD SCIENCE AND HUMAN WELLNESS
卷号	13 期号:2 页码:1055-1064
摘要	Wild edible Termitomyces mushrooms are popular in Southwest China and umami is important flavor qualities of edible mushrooms. This study aimed to understand the umami taste of Termitomyces intermedius and Termitomyces aff. bulborhizus. Ten umami peptides from aqueous extracts were separated using a Sephadex G-15 gel filtration chromatography. The intense umami fraction was evaluated by both sensory evaluation and electronic tongue. They were identified as KLNDAQAPK, DSTDEKFLR, VGKGAHLSGEH, MLKKKKLA, SLGFGGPPGY, TVATFSSSTKPDD, AMDDDEADLLLLAM, VEDEDEKPKEK, SPEEKKEEET and PEGADKPNK. Seven peptides, except VEDEDEKPKEK, SPEEKKEEET and PEGADKPNK were selectively synthesized to verify their taste characteristics. All these 10 peptides had umami or salt taste. The 10 peptides were conducted by molecular docking to study their interaction with identified peptides and the umami taste receptor T1R1/T1R3. All these 10 peptides perfectly docked the active residues in the T1R3 subunit. Our results provide theoretical basis for the umami taste and address the umami mechanism of two wild edible Termitomyces mushrooms. (c) 2024 Beijing Academy of Food Sciences. Publishing services by Tsinghua University Press.
DOI	10.26599/FSHW.2022.9250091
WOS记录号	WOS:001092234000003
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75841
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Zhang, Lanyun,Zhang, Li,Perez-Moreno, Jesus,et al. Novel umami peptides from two Termitomyces mushrooms and molecular docking to the taste receptor T1R1/T1R3[J]. FOOD SCIENCE AND HUMAN WELLNESS,2024,13(2):1055-1064.
APA	Zhang, Lanyun,Zhang, Li,Perez-Moreno, Jesus,Bin, Lu,Zhang, Fengming,&Yu, Fuqiang.(2024).Novel umami peptides from two Termitomyces mushrooms and molecular docking to the taste receptor T1R1/T1R3.FOOD SCIENCE AND HUMAN WELLNESS,13(2),1055-1064.
MLA	Zhang, Lanyun,et al."Novel umami peptides from two Termitomyces mushrooms and molecular docking to the taste receptor T1R1/T1R3".FOOD SCIENCE AND HUMAN WELLNESS 13.2(2024):1055-1064.

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