Undescribed Cyclohexene and Benzofuran Alkenyl Derivatives from Choerospondias axillaris, a Potential Hypoglycemic Fruit

doi:10.3390/foods13101495

KIB OpenIR

	Undescribed Cyclohexene and Benzofuran Alkenyl Derivatives from Choerospondias axillaris, a Potential Hypoglycemic Fruit
	Weldetsadik, Ermias Tamiru; Li, Na; Li, Jingjuan; Shang, Jiahuan; Zhu, Hongtao; Zhang, Yingjun
	2024
发表期刊	FOODS
卷号	13 期号:10 页码:1495
摘要	The fruit of Choerospondias axillaris (Anacardiaceae), known as south wild jujube in China, has been consumed widely in several regions of the world to produce fruit pastille and leathers, juice, jam, and candy. A comprehensive chemical study on the fresh fruits led to the isolation and identification of 18 compounds, including 7 new (1-7) and 11 known (8-18) comprised of 5 alkenyl (cyclohexenols and cyclohexenones) derivatives (1-5), 3 benzofuran derivatives (6-8), 6 flavonoids (9-14) and 4 lignans (15-18). Their structures were elucidated by extensive spectroscopic analysis. The known lignans 15-18 were isolated from the genus Choerospondias for the first time. Most of the isolates exhibited significant inhibitory activity on alpha-glucosidase with IC50 values from 2.26 +/- 0.06 to 43.9 +/- 0.96 mu M. Molecular docking experiments strongly supported the potent alpha-glucosidase inhibitory activity. The results indicated that C. axillaris fruits could be an excellent source of functional foods that acquire potential hypoglycemic bioactive components.
DOI	10.3390/foods13101495
WOS记录号	WOS:001233290800001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75803
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Weldetsadik, Ermias Tamiru,Li, Na,Li, Jingjuan,et al. Undescribed Cyclohexene and Benzofuran Alkenyl Derivatives from Choerospondias axillaris, a Potential Hypoglycemic Fruit[J]. FOODS,2024,13(10):1495.
APA	Weldetsadik, Ermias Tamiru,Li, Na,Li, Jingjuan,Shang, Jiahuan,Zhu, Hongtao,&Zhang, Yingjun.(2024).Undescribed Cyclohexene and Benzofuran Alkenyl Derivatives from Choerospondias axillaris, a Potential Hypoglycemic Fruit.FOODS,13(10),1495.
MLA	Weldetsadik, Ermias Tamiru,et al."Undescribed Cyclohexene and Benzofuran Alkenyl Derivatives from Choerospondias axillaris, a Potential Hypoglycemic Fruit".FOODS 13.10(2024):1495.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
10.3390_foods1310149（2185KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	浏览下载