Performing 2D-1D-2D Mass Spectrometry Imaging Using Strings

doi:10.1021/acs.analchem.1c04181

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	Performing 2D-1D-2D Mass Spectrometry Imaging Using Strings
	Wang, Yu; Xia, Bing; Deng, Shunyan; Ye, Ye; Zhou, Yan
	2022
发表期刊	ANALYTICAL CHEMISTRY
卷号	94 期号:3 页码:1661-1668
摘要	The mass spectrometry imaging (MSI) technique is widely used in several fields due to its ability to provide spatial information of samples. However, for existing MSI methods, the sample is typically placed on a two-dimensional (2D) platform and is scanned back and forth. As a result, the platform size limits the imaging size. This paper proposes a new MSI method that involves the initial imprinting of chemicals on a two-dimensional string plane area. The string plane was then unraveled to a onedimensional (1D) string, and the chemicals imprinted on it were ionized using a lab-made ion source. Finally, a 2D MSI image was reconstructed through data processing (2D-1D-2D mass imaging). Compared with traditional MSI methods, the imaging size is no longer limited by the platform size, making it possible to perform the MSI of large samples. As proof of concept, this method was used to image an intact seedling of Broussonetia papyrifera. As a result, clear and overall MS images were obtained, demonstrating the ability of this method to analyze large samples.
关键词	BROUSSONETIA-PAPYRIFERA PLANT METABOLITES SINGLE CELLS SIMS
DOI	10.1021/acs.analchem.1c04181
收录类别	SCI
WOS记录号	WOS:000768174600001
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75667
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Wang, Yu,Xia, Bing,Deng, Shunyan,et al. Performing 2D-1D-2D Mass Spectrometry Imaging Using Strings[J]. ANALYTICAL CHEMISTRY,2022,94(3):1661-1668.
APA	Wang, Yu,Xia, Bing,Deng, Shunyan,Ye, Ye,&Zhou, Yan.(2022).Performing 2D-1D-2D Mass Spectrometry Imaging Using Strings.ANALYTICAL CHEMISTRY,94(3),1661-1668.
MLA	Wang, Yu,et al."Performing 2D-1D-2D Mass Spectrometry Imaging Using Strings".ANALYTICAL CHEMISTRY 94.3(2022):1661-1668.

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