Three new quinolizidine alkaloids from the roots of Sophora tonkinensis

doi:10.1080/10286020.2023.2221658

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	Three new quinolizidine alkaloids from the roots of Sophora tonkinensis
	An,Qiao; Zhang,Ji; Zhang,Peng; Chen,Lei; Yi,Ping; Yuan,Chun-Mao; Hu,Zhan-Xing; Hao,Xiao-Jiang
	2023
发表期刊	JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
ISSN	1477-2213
摘要	Three new quinolizidine alkaloids (1 - 3), including one new naturally isoflavone and cytisine polymer (3), along with 6 known ones were isolated from the ethanol extract of Sophora tonkinensis Gagnep. Their structures were elucidated by comprehensive spectroscopic data analysis (IR, UV, HRESIMS, 1D and 2D NMR), combined with ECD calculations. The antifungal activity against Phytophythora capsica, Botrytis cinerea, Gibberella zeae, and Alternaria alternata of the compounds was evaluated in a mycelial inhibition assay. Biological tests indicated that compound 3 exhibited strong antifungal activity against P. capsica with EC50 values of 17.7 mu g/ml.
关键词	Fabaceae Sophora tonkinensis quinolizidine alkaloids antifungal activity MATRINE-TYPE ALKALOIDS SEEDS
学科领域	Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
DOI	10.1080/10286020.2023.2221658
收录类别	SCI
WOS记录号	WOS:001005910300001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75609
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	An,Qiao,Zhang,Ji,Zhang,Peng,et al. Three new quinolizidine alkaloids from the roots of Sophora tonkinensis[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2023.
APA	An,Qiao.,Zhang,Ji.,Zhang,Peng.,Chen,Lei.,Yi,Ping.,...&Hao,Xiao-Jiang.(2023).Three new quinolizidine alkaloids from the roots of Sophora tonkinensis.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH.
MLA	An,Qiao,et al."Three new quinolizidine alkaloids from the roots of Sophora tonkinensis".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2023).

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