Active constituents with α-glucosidase inhibitory activities from Sabia parviflora

doi:10.1016/j.fitote.2023.105516

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	Active constituents with α-glucosidase inhibitory activities from Sabia parviflora
	Hong,Qi-hui; Li,Jiang; Deng,Lu-lu; Hao,Xiao-jiang; Mu,Shu-zhen
	2023
发表期刊	FITOTERAPIA
ISSN	1873-6971
卷号	167 页码:105516
摘要	To identify the active constituents with alpha-glucosidase inhibitory activities in Sabia parviflora, three new compounds, namely, sabiaparviflora A-C (1, 2 and 8), and seven known compounds were isolated from the plant by repeated column chromatography. The structures of the new compounds were identified by extensive application of spectroscopic methods, including H-1 NMR, C-13 NMR, IR and HR-ESI-MS. All compounds, except for compounds 3-5, 9 and 10 were isolated for the first time from S. parviflora. Their alpha-glucosidase inhibitory activities were evaluated for the first time by the PNPG method. Three compounds (1, 7 and 10) exhibited marked activities, with IC50 values ranging from 104 to 324 mu M, and their structure-activity relationship is preliminarily discussed herein.
关键词	Sabia parviflora alpha-Glucosidase inhibitory activities Aporphine alkaloids Pentacyclic triterpenoids
DOI	10.1016/j.fitote.2023.105516
收录类别	SCI
WOS记录号	WOS:000992059400001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75510
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Hong,Qi-hui,Li,Jiang,Deng,Lu-lu,et al. Active constituents with α-glucosidase inhibitory activities from Sabia parviflora[J]. FITOTERAPIA,2023,167:105516.
APA	Hong,Qi-hui,Li,Jiang,Deng,Lu-lu,Hao,Xiao-jiang,&Mu,Shu-zhen.(2023).Active constituents with α-glucosidase inhibitory activities from Sabia parviflora.FITOTERAPIA,167,105516.
MLA	Hong,Qi-hui,et al."Active constituents with α-glucosidase inhibitory activities from Sabia parviflora".FITOTERAPIA 167(2023):105516.

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