Triterpenoids from the fruits of Aphanamixis polystachya and their inhibitory activities on nitric oxide production

doi:10.1016/j.fitote.2023.105709

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	Triterpenoids from the fruits of Aphanamixis polystachya and their inhibitory activities on nitric oxide production
	Yang,Xing; Wu,Shi-Li; Li,Bao-Jing; Li,Yan-Ping; He,Hong-Ping; Dong,Fa-Wu
	2023
发表期刊	FITOTERAPIA
ISSN	1873-6971
卷号	171 页码:105709
摘要	Nineteen triterpenoids, including five previously unknown (four triucallane-type derivatives and one highly oxidized A, B-seco limonoids), together with fourteen known triterpenoids, were isolated from the fruits of Aphanamixis polystachya. Their structures were elucidated by extensive spectroscopic analysis. All isolates were evaluated their anti-inflammatory activities. The result showed that all compounds inhibit LPS-induced nitric oxide production in RAW264.7 macrophages with their IC50 value ranging from 95 to 1332 uM, and compound 6 exhibited obvious anti-inflammatory activity comparable to that of the positive control, with IC50 values of 94.96 uM.
关键词	Meliaceae Aphanamixis polystachya Triterpenoids Nitric oxide LIMONOIDS SEED
DOI	10.1016/j.fitote.2023.105709
收录类别	SCI
WOS记录号	WOS:001102436700001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75506
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Yang,Xing,Wu,Shi-Li,Li,Bao-Jing,et al. Triterpenoids from the fruits of Aphanamixis polystachya and their inhibitory activities on nitric oxide production[J]. FITOTERAPIA,2023,171:105709.
APA	Yang,Xing,Wu,Shi-Li,Li,Bao-Jing,Li,Yan-Ping,He,Hong-Ping,&Dong,Fa-Wu.(2023).Triterpenoids from the fruits of Aphanamixis polystachya and their inhibitory activities on nitric oxide production.FITOTERAPIA,171,105709.
MLA	Yang,Xing,et al."Triterpenoids from the fruits of Aphanamixis polystachya and their inhibitory activities on nitric oxide production".FITOTERAPIA 171(2023):105709.

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