Three new isoquinoline alkaloids from the cigar tobacco-derived endophytic fungus Aspergillus felis

doi:10.1016/j.phytol.2023.05.006

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	Three new isoquinoline alkaloids from the cigar tobacco-derived endophytic fungus Aspergillus felis
	Ma,Yue-Yu; Pu,Gui; Cha,Xue-Ju; Xiong,Rui-Feng; Zhang,Guang-Hai; Yao,Heng; Bao,Mei-Fen; Kong,Guang-Hui; Li,Yin-Ke; Hu,Qiu-Fen; Wu,Yu-Ping
	2023
发表期刊	PHYTOCHEMISTRY LETTERS
ISSN	1876-7486
卷号	55 页码:137-141
摘要	The isoquinoline alkaloids have attracted widespread attention from chemists and biologists due to their complex structures and prominent bioactivities. With the aims of screening for antiviral compounds produced by fungi, in this study, three new (1-3), together with four known (4-7) isoquinolines were isolated from the cigar tobaccoderived endophytic fungus Aspergillus felis. Their structures were determined by means of HRESIMS and NMR spectroscopic studies. Interestingly, an anti-TMV test revealed that compounds 2 and 4 showed high activity with inhibition rates of 43.2% and 38.4%, respectively. These rates are higher than those of the positive control ningnanmycin (33.2%). The isolation of the above isoquinolines may provide materials for the study of more potent anti-TMV inhibitors and contribute to an improved utilization of cigar tobacco-derived endophytic fungi.
关键词	Isoquinolines Alkaloids Aspergillus felis Anti -tobacco mosaic virus (anti-TMV) activity
学科领域	Plant Sciences ; Pharmacology & Pharmacy
DOI	10.1016/j.phytol.2023.05.006
收录类别	SCI
WOS记录号	WOS:001001935000001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75423
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Ma,Yue-Yu,Pu,Gui,Cha,Xue-Ju,et al. Three new isoquinoline alkaloids from the cigar tobacco-derived endophytic fungus Aspergillus felis[J]. PHYTOCHEMISTRY LETTERS,2023,55:137-141.
APA	Ma,Yue-Yu.,Pu,Gui.,Cha,Xue-Ju.,Xiong,Rui-Feng.,Zhang,Guang-Hai.,...&Wu,Yu-Ping.(2023).Three new isoquinoline alkaloids from the cigar tobacco-derived endophytic fungus Aspergillus felis.PHYTOCHEMISTRY LETTERS,55,137-141.
MLA	Ma,Yue-Yu,et al."Three new isoquinoline alkaloids from the cigar tobacco-derived endophytic fungus Aspergillus felis".PHYTOCHEMISTRY LETTERS 55(2023):137-141.

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