Enantioselective Total Synthesis of the Cephalotaxus Alkaloid (-)-Cephalotine A

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	Enantioselective Total Synthesis of the Cephalotaxus Alkaloid (-)-Cephalotine A
	Sheng,Peng-Zhen; Li,Lu-Lu; Ni,Zhi-Bin; Wei,Kun; Yang,Yu-Rong
	2023
发表期刊	ORGANIC LETTERS
ISSN	1523-7052
摘要	Cephalotine A, a recently isolated Cephalotaxus alkaloid,was firstsynthesized enantioselectively through three critical reactions. SmI2 -mediated radical cyclization of lactone and aldehyde toforge the final ring system, Chang's iridium-catalyzed C-Hamidation to construct pyrrolidone stereoselectively, and Carreria'sdual Ir/amine catalyzed allylation to install the vicinal tertiarystereocenters.
关键词	FORMAL TOTAL-SYNTHESIS ALPHA-ALLYLATION UNIFIED STRATEGY NATURAL-PRODUCTS GAMMA-LACTAMS HECK REACTION (+/-)-CEPHALOTAXINE REARRANGEMENT C
DOI	10.1021/acs.orglett.3c02097
收录类别	SCI
WOS记录号	WOS:001047853100001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75283
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Sheng,Peng-Zhen,Li,Lu-Lu,Ni,Zhi-Bin,et al. Enantioselective Total Synthesis of the Cephalotaxus Alkaloid (-)-Cephalotine A[J]. ORGANIC LETTERS,2023.
APA	Sheng,Peng-Zhen,Li,Lu-Lu,Ni,Zhi-Bin,Wei,Kun,&Yang,Yu-Rong.(2023).Enantioselective Total Synthesis of the Cephalotaxus Alkaloid (-)-Cephalotine A.ORGANIC LETTERS.
MLA	Sheng,Peng-Zhen,et al."Enantioselective Total Synthesis of the Cephalotaxus Alkaloid (-)-Cephalotine A".ORGANIC LETTERS (2023).