Modular and Stereoselective One-Pot Total Synthesis of Icosasaccharide Motif from Cordyceps sinensis EPS-1A Glycan

doi:10.1021/acs.orglett.3c02842

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	Modular and Stereoselective One-Pot Total Synthesis of Icosasaccharide Motif from Cordyceps sinensis EPS-1A Glycan
	Sun,Xingchun; Chen,Zhiyuan; Yang,Rui; Wang,Mei; Wang,Xiufang; Zhang,Qi; Xiao,Guozhi
	2023
发表期刊	ORGANIC LETTERS
ISSN	1523-7052
卷号	25 期号:40 页码:7364-7368
摘要	The first stereoselective one-pot synthesis of the icosasaccharide motif of EPS-1A glycan from Cordyceps sinensis has been achieved. The synthetic approach highlights the following features: (1) merging reagent modulation and remote anchimeric assistance alpha-glycosylation strategy for the highly stereoselective formation of five and ten continuous 1,2-cis glucosidic bonds; (2) the strategic employment of glycosyl N-phenyltrifluoroacetimidates and glycosyl o-(1-phenylvinyl)benzoates as the matched pair for efficient orthogonal one-pot synthesis; and (3) [11 + 8 + 1] orthogonal one-pot glycosylation for the efficient assembly of the target icosasaccharide.
关键词	MYCELIAL FERMENTATION GLYCOSYLATION POLYSACCHARIDES
DOI	10.1021/acs.orglett.3c02842
收录类别	SCI
WOS记录号	WOS:001077689500001
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75281
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Sun,Xingchun,Chen,Zhiyuan,Yang,Rui,et al. Modular and Stereoselective One-Pot Total Synthesis of Icosasaccharide Motif from Cordyceps sinensis EPS-1A Glycan[J]. ORGANIC LETTERS,2023,25(40):7364-7368.
APA	Sun,Xingchun.,Chen,Zhiyuan.,Yang,Rui.,Wang,Mei.,Wang,Xiufang.,...&Xiao,Guozhi.(2023).Modular and Stereoselective One-Pot Total Synthesis of Icosasaccharide Motif from Cordyceps sinensis EPS-1A Glycan.ORGANIC LETTERS,25(40),7364-7368.
MLA	Sun,Xingchun,et al."Modular and Stereoselective One-Pot Total Synthesis of Icosasaccharide Motif from Cordyceps sinensis EPS-1A Glycan".ORGANIC LETTERS 25.40(2023):7364-7368.

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