Pentacyclic Triterpenoids from Sabia discolor Dunn and Their alpha-Glycosidase Inhibitory Activities

doi:10.3390/molecules27072161

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	Pentacyclic Triterpenoids from Sabia discolor Dunn and Their alpha-Glycosidase Inhibitory Activities
	Ma, Jin-Hong; Hu, Dan; Deng, Lu-Lu; Li, Jiang; Hao, Xiao-Jiang; Mu, Shu-Zhen
	2022
发表期刊	MOLECULES
卷号	27 期号:7 页码:2161
摘要	Four new pentacyclic triterpenoids named Sabiadiscolor A-D (1 and 7-9) together with eleven known ones were isolated by repeated column chromatography. Their structures were identified and characterized by NMR and MS spectral data as 6 oleanane-type pentacyclic triterpenoids (1-6), 7 ursane-type ones (7-13), and 2 lupanane-type ones (14-15). Except for compound 15, all other compounds were isolated from Sabia discolor Dunn for the first time. Their alpha-glycosidase inhibitory activities were evaluated, which showed that compounds 1, 3, 8, 9, 13, and 15 implied remarkable activities with IC50 values ranging from 0.09 to 0.27 mu M, and the preliminary structure-activity relationship was discussed.
关键词	Sabia discolor Dunn pentacyclic triterpenoids isolation and purification alpha-glycosidase inhibitory activities
DOI	10.3390/molecules27072161
收录类别	SCI
WOS记录号	WOS:000781711200001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/74777
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Ma, Jin-Hong,Hu, Dan,Deng, Lu-Lu,et al. Pentacyclic Triterpenoids from Sabia discolor Dunn and Their alpha-Glycosidase Inhibitory Activities[J]. MOLECULES,2022,27(7):2161.
APA	Ma, Jin-Hong,Hu, Dan,Deng, Lu-Lu,Li, Jiang,Hao, Xiao-Jiang,&Mu, Shu-Zhen.(2022).Pentacyclic Triterpenoids from Sabia discolor Dunn and Their alpha-Glycosidase Inhibitory Activities.MOLECULES,27(7),2161.
MLA	Ma, Jin-Hong,et al."Pentacyclic Triterpenoids from Sabia discolor Dunn and Their alpha-Glycosidase Inhibitory Activities".MOLECULES 27.7(2022):2161.

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