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Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz.
Zhang,Na; Xia,Fan; Li,Song-Yu; Nian,Yin; Wei,Li-Xin; Xu,Gang
2021
发表期刊Natural products and bioprospecting
ISSN2192-2195
卷号11期号:4页码:421-429
摘要Sixteen diterpenoid alkaloids (DAs), including six aconitine-type alkaloids (5 and 9-13), seven 7,17-seco-aconitine-type alkaloids (1-4, 6-8), two napelline-type alkaloids (14 and 15) as well as one veatchine-type alkaloid (16), were isolated from the aerial parts of Aconitum flavum Hand.-Mazz. In which, flavumolines A-D (1-4) were four new ones, and flavumoline E (5) was reported as natural compound for the first time. Their chemical structures were elucidated by the analysis of extensive spectroscopic data. The inhibitory activities of these isolates on Cav3.1 low voltage-gated Ca2+ channel, NO production in LPS-activated RAW264.7cells, five human tumor cell lines, as well as acetylcholinesterase (AChE) were tested.
DOI10.1007/s13659-021-00302-3
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/73803
专题中国科学院昆明植物研究所
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Zhang,Na,Xia,Fan,Li,Song-Yu,et al. Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz.[J]. Natural products and bioprospecting,2021,11(4):421-429.
APA Zhang,Na,Xia,Fan,Li,Song-Yu,Nian,Yin,Wei,Li-Xin,&Xu,Gang.(2021).Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz..Natural products and bioprospecting,11(4),421-429.
MLA Zhang,Na,et al."Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz.".Natural products and bioprospecting 11.4(2021):421-429.
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