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Isoprenylated Flavonoids as Cav3.1 Low Voltage-Gated Ca2+ Channel Inhibitors from Salvia digitaloides.
Zhao,Jian-Jun; Li,Song-Yu; Xia,Fan; Hu,Ya-Li; Nian,Yin; Xu,Gang
2021
发表期刊Natural products and bioprospecting
ISSN2192-2195
卷号11期号:6页码:671-678
摘要Saldigones A-C (1, 3, 4), three new isoprenylated flavonoids with diverse flavanone, pterocarpan, and isoflavanone architectures, were characterized from the roots of Salvia digitaloides, together with a known isoprenylated flavanone (2). Notably, it's the first report of isoprenylated flavonoids from Salvia species. The structures of these isolates were elucidated by extensive spectroscopic analysis. All of the compounds were evaluated for their activities on Cav3.1 low voltage-gated Ca2+ channel (LVGCC), of which 2 strongly and dose-dependently inhibited Cav3.1 peak current.
DOI10.1007/s13659-021-00307-y
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/73801
专题中国科学院昆明植物研究所
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Zhao,Jian-Jun,Li,Song-Yu,Xia,Fan,et al. Isoprenylated Flavonoids as Cav3.1 Low Voltage-Gated Ca2+ Channel Inhibitors from Salvia digitaloides.[J]. Natural products and bioprospecting,2021,11(6):671-678.
APA Zhao,Jian-Jun,Li,Song-Yu,Xia,Fan,Hu,Ya-Li,Nian,Yin,&Xu,Gang.(2021).Isoprenylated Flavonoids as Cav3.1 Low Voltage-Gated Ca2+ Channel Inhibitors from Salvia digitaloides..Natural products and bioprospecting,11(6),671-678.
MLA Zhao,Jian-Jun,et al."Isoprenylated Flavonoids as Cav3.1 Low Voltage-Gated Ca2+ Channel Inhibitors from Salvia digitaloides.".Natural products and bioprospecting 11.6(2021):671-678.
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