Assessment of veterinary antibiotics from animal manure-amended soil to growing alfalfa, alfalfa silage, and milk

doi:10.1016/j.ecoenv.2021.112699

KIB OpenIR

	Assessment of veterinary antibiotics from animal manure-amended soil to growing alfalfa, alfalfa silage, and milk
	Huang,Rongcai ; Guo,Zitai ; Gao,Shengtao ; Ma,Lu ; Xu,Jianchu; Yu,Zhongtang ; Bu,Dengpan
	2021
发表期刊	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
ISSN	0147-6513
卷号	224 页码:112699
摘要	Using animal manure as organic fertilizer to grow fodder crops is causing public health concerns because animal manure is the major reservoir of veterinary antibiotics. In this study, we used a mathematical model to estimate the risk of human exposure to veterinary antibiotics when using swine manure as organic fertilizer to grow alfalfa (Medicago sativa L.). Alfalfa was planted in a greenhouse and fertilized with swine manure spiked with oxytetracycline (OTC, at 0, 150, and 1500 mg/kg of manure), ofloxacin (OFL, at 0, 15, and 150 mg/kg), or sulfamonomethoxine (SMM, at 0, 5, 15 and 150 mg/kg). Alfalfa was harvested at the budding stage and ensiled for 60 days. Results showed that OTC and OFL could be detected in the alfalfa root, stem, and leaf with a concentration ranging from 8.85 to 59.17 mu g OTC /kg and from 1.50 to 4.10 mu g OFL/kg dry matter, but SMM could only be detected in the root ranging from 29.10 to 63.75 mu g/kg dry matter. The ensiling for 60 days decreased the OFL concentration by 68.7% but only slightly decreased the OTC concentration. The maximum daily exposures of humans to OTC and OFL through liquid milk consumption were estimated to be 5.84E-8 and 1.63E-8 mu g, respectively, both of which are well below the intake levels of OTC (72 mu g) and OFL (54 mu g) mandated by the European Union. The results of the present study indicate that using swine manure as organic fertilizer to grow alfalfa poses a limited risk for human exposure to veterinary antibiotics through the consumption of liquid milk.
关键词	Alfalfa Organic fertilizer Exposure assessment Milk Veterinary antibiotic PERSONAL CARE PRODUCTS WASTE-WATER AGRICULTURAL SOILS RESISTANCE GENES PLANT UPTAKE CROPS RESIDUES RISKS TETRACYCLINES PERFORMANCE
DOI	10.1016/j.ecoenv.2021.112699
WOS记录号	WOS:000694707800006
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73781
专题	中国科学院昆明植物研究所
作者单位	1.Chinese Acad Agr Sci, Inst Anim Sci, State Key Lab Anim Nutr, Beijing 100193, Peoples R China 2.World Agroforestry Ctr, Kunming 650201, Yunnan, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Honghe Ctr Mt Futures, Kunming 654400, Yunnan, Peoples R China 4.Ohio State Univ, Dept Anim Sci, Columbus, OH 43210 USA 5.World Agroforestry Ctr, CAAS ICRAF Joint Lab Agroforestry & Sustainable A, Beijing 100081, Peoples R China 6.Hunan Coinnovat Ctr Anim Prod Safety, Changsha 410128, Hunan, Peoples R China
推荐引用方式 GB/T 7714	Huang,Rongcai,Guo,Zitai,Gao,Shengtao,et al. Assessment of veterinary antibiotics from animal manure-amended soil to growing alfalfa, alfalfa silage, and milk[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2021,224:112699.
APA	Huang,Rongcai.,Guo,Zitai.,Gao,Shengtao.,Ma,Lu.,Xu,Jianchu.,...&Bu,Dengpan.(2021).Assessment of veterinary antibiotics from animal manure-amended soil to growing alfalfa, alfalfa silage, and milk.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,224,112699.
MLA	Huang,Rongcai,et al."Assessment of veterinary antibiotics from animal manure-amended soil to growing alfalfa, alfalfa silage, and milk".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 224(2021):112699.