Ten picrotoxane-type sesquiterpenoids from the stems of Dendrobium wardianum Warner
Fan,Wei-Wei; Yang,Dan; Cheng,Zhong-Quan; Xu,Feng-Qing; Dong,Fa-Wu; Wei,Xiao-Yong; Hu,Jiang-Miao
Source PublicationPHYTOCHEMISTRY
AbstractTen undescribed picrotoxane-type sesquiterpenoids, dendrowardins A-J, together with two known ones, were isolated from the stems of Dendrobium wardianum Warner (Orchidaceae). Dendrowardins A-D feature the unusual 5,2-6-lactone and additionally dendrowardins C-D are the first examples containing the 11,10-gamma-lactone moiety. The structures were established using spectroscopic methods and by comparison with literature data. Further, dendrowardin E, amotin, and aduncin exhibited significant effects of promoting the proliferation on human lens epithelial cells (HLECs) induced by D-galactose.
KeywordDendrobium wardianum Orchidaceae Picrotoxane-type sesquiterpenoid Dendrowardins A-J
WOS IDWOS:000687218600010
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Document Type期刊论文
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Pingdingshan Univ, Coll Med, Henan Engn Res Ctr Funiu Mt Med Resources Utiliza, Pingdingshan 467000, Peoples R China
3.Guangdong Med Univ, Coll Pharm, Dongguan 523808, Peoples R China
4.Guangzhou Hlth Sci Coll, Coll Pharm, Guangzhou 510450, Peoples R China
5.Guangzhou Univ Chinese Med, Coll Pharm, Guangzhou 510006, Peoples R China
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Fan,Wei-Wei,Yang,Dan,Cheng,Zhong-Quan,et al. Ten picrotoxane-type sesquiterpenoids from the stems of Dendrobium wardianum Warner[J]. PHYTOCHEMISTRY,2021,190:112858.
APA Fan,Wei-Wei.,Yang,Dan.,Cheng,Zhong-Quan.,Xu,Feng-Qing.,Dong,Fa-Wu.,...&Hu,Jiang-Miao.(2021).Ten picrotoxane-type sesquiterpenoids from the stems of Dendrobium wardianum Warner.PHYTOCHEMISTRY,190,112858.
MLA Fan,Wei-Wei,et al."Ten picrotoxane-type sesquiterpenoids from the stems of Dendrobium wardianum Warner".PHYTOCHEMISTRY 190(2021):112858.
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