Phenylhydrazone and Quinazoline Derivatives from the Cold-Seep-Derived Fungus Penicillium oxalicum

doi:10.3390/md19010009

KIB OpenIR

	Phenylhydrazone and Quinazoline Derivatives from the Cold-Seep-Derived Fungus Penicillium oxalicum
	Liu,Ya-Ping ; Fang,Sheng-Tao ; Shi,Zhen-Zhen ; Wang,Bin-Gui ; Li,Xiao-Nian ; Ji,Nai-Yun
	2021
发表期刊	MARINE DRUGS
ISSN	1660-3397
卷号	19 期号:1 页码:9
摘要	Three new phenylhydrazones, penoxahydrazones A-C (compounds 1-3), and two new quinazolines, penoxazolones A (compound 4) and B (compound 5), with unique linkages were isolated from the fungus Penicillium oxalicum obtained from the deep sea cold seep. Their structures and relative configurations were assigned by analysis of 1D/2D NMR and mass spectroscopic data, and the absolute configurations of 1, 4, and 5 were established on the basis of X-ray crystallography or ECD calculations. Compound 1 represents the first natural phenylhydrazone-bearing steroid, while compounds 2 and 3 are rarely occurring phenylhydrazone tautomers. Compounds 4 and 5 are enantiomers that feature quinazoline and cinnamic acid units. Some isolates exhibited inhibition of several marine phytoplankton species and marine-derived bacteria.
关键词	Penicillium oxalicum deep sea cold seep phenylhydrazone quinazoline
DOI	10.3390/md19010009
WOS记录号	WOS:000611035300001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73589
专题	中国科学院昆明植物研究所
作者单位	1.[Liu, Ya-Ping 2.Fang, Sheng-Tao 3.Shi, Zhen-Zhen 4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Ctr Ocean Mega Sci, Yantai 264003, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.Chinese Acad Sci, Qingdao Natl Lab Marine Sci & Technol, Ctr Ocean Mega Sci, Inst Oceanol,Key Lab Expt Marine Biol,Lab Marine, Qingdao 266071, Peoples R China 7.Chinese Acad Sci, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Liu,Ya-Ping,Fang,Sheng-Tao,Shi,Zhen-Zhen,et al. Phenylhydrazone and Quinazoline Derivatives from the Cold-Seep-Derived Fungus Penicillium oxalicum[J]. MARINE DRUGS,2021,19(1):9.
APA	Liu,Ya-Ping,Fang,Sheng-Tao,Shi,Zhen-Zhen,Wang,Bin-Gui,Li,Xiao-Nian,&Ji,Nai-Yun.(2021).Phenylhydrazone and Quinazoline Derivatives from the Cold-Seep-Derived Fungus Penicillium oxalicum.MARINE DRUGS,19(1),9.
MLA	Liu,Ya-Ping,et al."Phenylhydrazone and Quinazoline Derivatives from the Cold-Seep-Derived Fungus Penicillium oxalicum".MARINE DRUGS 19.1(2021):9.