New xanthones from Canscora lucidissima and their antioxidant and NO inhibitory activities

doi:10.1080/14786419.2021.1886099

KIB OpenIR

	New xanthones from Canscora lucidissima and their antioxidant and NO inhibitory activities
	Luo,Binsheng ; Huang,Kunhui ; Sui,Xianjin ; Wang,Miaomiao ; Long,Chunlin
	2022
发表期刊	NATURAL PRODUCT RESEARCH
ISSN	1478-6419
卷号	36 期号:6 页码:1433-1440
摘要	Three new xanthone glycosides, canlucosides A - C (1 - 3), along with three known compounds (4 - 6), have been obtained and identified from the ethanol extract of Canscora lucidissima. Their structures were identified according to HR-ESI-MS, 1D, 2D NMR data, ECD measurements powered by molecular calculations and optical rotation values. Compound 6 (1-hydroxy-3,7,8-trmethoxyxanthone) was isolated from C. lucidissima for the first time. Five compounds (2-6) showed moderate antioxidant and NO inhibitory activities. Canlucosides B and C (2 and 3) showed significant antioxidant activity with IC50 values of 33.64 +/- 5.60 mu M and 36.63 +/- 4.32 mu M, respectively. Canlucoside B (2) possessed a significant NO inhibitory effect with an IC50 value 0.92 mu M.
关键词	Ethnomedicine Canscora lucidissima canlucosides A– C antioxidant activity NO inhibitory effects
DOI	10.1080/14786419.2021.1886099
WOS记录号	WOS:000617638800001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73444
专题	中国科学院昆明植物研究所
作者单位	1.Minzu Univ China, Coll Life & Environm Sci, Beijing, Peoples R China 2.Minzu Univ China, Minist Educ, Key Lab Ethnomed, Beijing, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Kunming, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Luo,Binsheng,Huang,Kunhui,Sui,Xianjin,et al. New xanthones from Canscora lucidissima and their antioxidant and NO inhibitory activities[J]. NATURAL PRODUCT RESEARCH,2022,36(6):1433-1440.
APA	Luo,Binsheng,Huang,Kunhui,Sui,Xianjin,Wang,Miaomiao,&Long,Chunlin.(2022).New xanthones from Canscora lucidissima and their antioxidant and NO inhibitory activities.NATURAL PRODUCT RESEARCH,36(6),1433-1440.
MLA	Luo,Binsheng,et al."New xanthones from Canscora lucidissima and their antioxidant and NO inhibitory activities".NATURAL PRODUCT RESEARCH 36.6(2022):1433-1440.