A review of plant characteristics, phytochemistry and bioactivities of the genus Glechoma
Zhou,Ying; He,Ying-Jie; Wang,Zhao-Jie; Hu,Bin-Yuan; Xie,Tian-Zhen; Xiao,Xia; Zhou,Zhong-Shun; Sang,Xu-Yan; Luo,Xiao-Dong
AbstractEthnopharmacological relevance: Plants of the genus Glechoma have been abundantly used for thousands of years in China as folk treatments for cholelithiasis, urolithiasis, inflammation, and other conditions. Aim of the study: This review discusses the potential application of Glechoma as an herbal medicine. The plant characteristics, ethnobotanical uses, phytochemistry, and pharmacological activities of Glechoma are summarized as a guide for phytochemical and pharmacological investigations. Materials and methods: Various search engines including SciFinder, Google Scholar, Scopus-Elsevier, Medline, Web of Science, and China National Knowledge Infrastructure were searched for publications on Glechoma using relevant keywords. Additionally, local records, books, and non-English journals were screened up to October 2020. Results: The phytochemistry of several Glechoma plants has been systematically studied, and over one hundred different compounds have been isolated and identified. Terpenoids, flavonoids and polyphenols are the major secondary metabolites. Crude extracts and isolated compounds have been shown to exhibit various pharmacological activities including prevention of nephrolithiasis, anti-inflammatory, analgesic, anticomplement, antimicrobial, antioxidant, depigmenting, anticancer, and antiviral activities, among others. Conclusion: Glechoma species have been used as folk medicine to treat various diseases and have diverse biological activities, making them valuable starting materials for drug development. However, in most cases the pharmacological mechanisms, pharmacokinetics, toxicology, safety, and possible interactions with other drugs remain to be determined.
KeywordGlechoma Plant characteristics Phytochemistry Ethnobotanical uses Pharmacological activities
WOS IDWOS:000625359800003
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Document Type期刊论文
Affiliation1.[Zhou, Ying
2.He, Ying-Jie
3.Wang, Zhao-Jie
4.Hu, Bin-Yuan
5.Xie, Tian-Zhen
6.Xiao, Xia
7.Zhou, Zhong-Shun
8.Sang, Xu-Yan
9.Yunnan Univ, Key Lab Med Chem Nat Resource, Minist Educ, Kunming 650091, Yunnan, Peoples R China
10.Yunnan Univ, Yunnan Prov Ctr Res & Dev Nat Prod, Kunming 650091, Yunnan, Peoples R China
11.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Yunnan, Peoples R China
12.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
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Zhou,Ying,He,Ying-Jie,Wang,Zhao-Jie,et al. A review of plant characteristics, phytochemistry and bioactivities of the genus Glechoma[J]. JOURNAL OF ETHNOPHARMACOLOGY,2021,271:113830.
APA Zhou,Ying.,He,Ying-Jie.,Wang,Zhao-Jie.,Hu,Bin-Yuan.,Xie,Tian-Zhen.,...&Luo,Xiao-Dong.(2021).A review of plant characteristics, phytochemistry and bioactivities of the genus Glechoma.JOURNAL OF ETHNOPHARMACOLOGY,271,113830.
MLA Zhou,Ying,et al."A review of plant characteristics, phytochemistry and bioactivities of the genus Glechoma".JOURNAL OF ETHNOPHARMACOLOGY 271(2021):113830.
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