Knowledge Management System of Kunming Institute of Botany,CAS
| A review of plant characteristics, phytochemistry and bioactivities of the genus Glechoma | |
Zhou,Ying; He,Ying-Jie; Wang,Zhao-Jie; Hu,Bin-Yuan; Xie,Tian-Zhen; Xiao,Xia; Zhou,Zhong-Shun; Sang,Xu-Yan; Luo,Xiao-Dong
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| 2021 | |
| Source Publication | JOURNAL OF ETHNOPHARMACOLOGY
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| ISSN | 0378-8741 |
| Volume | 271Pages:113830 |
| Abstract | Ethnopharmacological relevance: Plants of the genus Glechoma have been abundantly used for thousands of years in China as folk treatments for cholelithiasis, urolithiasis, inflammation, and other conditions. Aim of the study: This review discusses the potential application of Glechoma as an herbal medicine. The plant characteristics, ethnobotanical uses, phytochemistry, and pharmacological activities of Glechoma are summarized as a guide for phytochemical and pharmacological investigations. Materials and methods: Various search engines including SciFinder, Google Scholar, Scopus-Elsevier, Medline, Web of Science, and China National Knowledge Infrastructure were searched for publications on Glechoma using relevant keywords. Additionally, local records, books, and non-English journals were screened up to October 2020. Results: The phytochemistry of several Glechoma plants has been systematically studied, and over one hundred different compounds have been isolated and identified. Terpenoids, flavonoids and polyphenols are the major secondary metabolites. Crude extracts and isolated compounds have been shown to exhibit various pharmacological activities including prevention of nephrolithiasis, anti-inflammatory, analgesic, anticomplement, antimicrobial, antioxidant, depigmenting, anticancer, and antiviral activities, among others. Conclusion: Glechoma species have been used as folk medicine to treat various diseases and have diverse biological activities, making them valuable starting materials for drug development. However, in most cases the pharmacological mechanisms, pharmacokinetics, toxicology, safety, and possible interactions with other drugs remain to be determined. |
| Keyword | Glechoma Plant characteristics Phytochemistry Ethnobotanical uses Pharmacological activities |
| DOI | 10.1016/j.jep.2021.113830 |
| WOS ID | WOS:000625359800003 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/73424 |
| Collection | 中国科学院昆明植物研究所 |
| Affiliation | 1.[Zhou, Ying 2.He, Ying-Jie 3.Wang, Zhao-Jie 4.Hu, Bin-Yuan 5.Xie, Tian-Zhen 6.Xiao, Xia 7.Zhou, Zhong-Shun 8.Sang, Xu-Yan 9.Yunnan Univ, Key Lab Med Chem Nat Resource, Minist Educ, Kunming 650091, Yunnan, Peoples R China 10.Yunnan Univ, Yunnan Prov Ctr Res & Dev Nat Prod, Kunming 650091, Yunnan, Peoples R China 11.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Yunnan, Peoples R China 12.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China |
| Recommended Citation GB/T 7714 | Zhou,Ying,He,Ying-Jie,Wang,Zhao-Jie,et al. A review of plant characteristics, phytochemistry and bioactivities of the genus Glechoma[J]. JOURNAL OF ETHNOPHARMACOLOGY,2021,271:113830. |
| APA | Zhou,Ying.,He,Ying-Jie.,Wang,Zhao-Jie.,Hu,Bin-Yuan.,Xie,Tian-Zhen.,...&Luo,Xiao-Dong.(2021).A review of plant characteristics, phytochemistry and bioactivities of the genus Glechoma.JOURNAL OF ETHNOPHARMACOLOGY,271,113830. |
| MLA | Zhou,Ying,et al."A review of plant characteristics, phytochemistry and bioactivities of the genus Glechoma".JOURNAL OF ETHNOPHARMACOLOGY 271(2021):113830. |
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