Chemical constituents from plant endophytic fungus Alternaria alternata

doi:10.1080/14786419.2019.1639699

KIB OpenIR

	Chemical constituents from plant endophytic fungus Alternaria alternata
	Wang,Ju-Tao ; Ma,Zong-Hui ; Wang,Guo-Kai ; Xu,Feng-Qing ; Yu,Yang ; Wang,Gang ; Peng,Dai-Yin ; Liu,Jin-Song
	2021
发表期刊	NATURAL PRODUCT RESEARCH
ISSN	1478-6419
卷号	35 期号:7 页码:1199-1206
摘要	Five new natural compounds (1-5) along with four known ones, involving dibenzo-alpha-pyrone derivatives, a benzo-gamma-pyrone derivative and an amide-type compound were obtained from Alternaria alternata, an endophyte isolated from Paeonia lactiflora. The structures of these isolates were elucidated by intensive analysis of spectroscopic data including NMR, HRMS (ESI and EI), UV and IR spectra. Compounds (1-4) were evaluated for their cytotoxicities against five selected human tumourtumour cell lines (A-549, MDA-MB-231, MCF-7, KB and KB-VIN), and compound 3 exhibited activities against MDA-MB-231and MCF-7 with IC50 values of 20.1 mu M and 32.2 mu M.[GRAPHICS].
关键词	Alternaria alternata Paeonia lactiflora benzo-alpha-pyrone derivatives cytotoxic activity METABOLITES INHIBITOR ROOT SP.
DOI	10.1080/14786419.2019.1639699
WOS记录号	WOS:000478316400001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73383
专题	中国科学院昆明植物研究所
作者单位	1.Anhui Univ Chinese Med, Sch Pharm, Anhui Key Lab Modern Chinese Mat Med, Hefei, Anhui, Peoples R China 2.Synerget Innovat Ctr Anhui Authent Chinese Med Qu, Hefei, Anhui, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China 4.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Wang,Ju-Tao,Ma,Zong-Hui,Wang,Guo-Kai,et al. Chemical constituents from plant endophytic fungus Alternaria alternata[J]. NATURAL PRODUCT RESEARCH,2021,35(7):1199-1206.
APA	Wang,Ju-Tao.,Ma,Zong-Hui.,Wang,Guo-Kai.,Xu,Feng-Qing.,Yu,Yang.,...&Liu,Jin-Song.(2021).Chemical constituents from plant endophytic fungus Alternaria alternata.NATURAL PRODUCT RESEARCH,35(7),1199-1206.
MLA	Wang,Ju-Tao,et al."Chemical constituents from plant endophytic fungus Alternaria alternata".NATURAL PRODUCT RESEARCH 35.7(2021):1199-1206.